Cancer Cell Signaling: Selecting the Best Importin for the Job

New research from Sidney Kimmel Cancer Center at Jefferson member Gino Cingolani, PhD,┬árecently provided critical insights into the nuclear import of key signaling proteins, including those involved in tumorigenesis. For a vast array of cellular processes, numerous proteins must be imported and exported from the cell nucleus in a tightly regulated fashion. Typically, proteins that …