Half-Match Bone Marrow Transplant Procedure Yields Promising Outcomes for Cancer Patients

Half-matched bone marrow or stem cell transplants for blood cancer patients have typically been associated with disappointing clinical outcomes. However, a clinical trial conducted at the Kimmel Cancer Center at Jefferson testing its unique, two-step half-match procedure has produced some promising results: the probability of overall survival was 45 percent in all patients after three years …


Robert B. Den, M.D., Joins the Department of Radiation Oncology at Jefferson

Radiation oncologist Robert B. Den, M.D., recently joined Thomas Jefferson University Hospital as an attending physician, and was also named an assistant professor at Jefferson Medical College of Thomas Jefferson University in the Department of Radiation Oncology. Dr. Den is a clinical scientist who specializes in the treatment of prostate cancer, combining his laboratory research …


A Tumor Suppressor May Also Fight Obesity

The hormone receptor guanylyl cyclase C (GCC) has been established as a suppressor of colorectal cancer tumors, but new evidence from Thomas Jefferson University suggests it may also help fight one of the country’s biggest pandemics: obesity. Reporting in the August 25 online issue of the Journal of Clinical Investigation, Scott Waldman, M.D., Ph.D., chairman …


ADVANCE for Nurses Magazine Features KCC’s Senior Adult Oncology Center

The multidisciplinary staff at the Center assesses the many health challenges confronting senior adults and recommends a personalized cancer treatment plan for each patient. Jefferson staff members Pat Dugan, Vicki Squire and Barb Daulerio were interviewed for the article. The nursing magazine, ADVANCE for Nurses, put the spotlight recently on the Senior Adult Oncology Center …


Blocking Receptor in Key Hormone Fires Up Enzyme to Kill Pancreatic Cancer Cells

Pancreatic cancer researchers at Thomas Jefferson University have shown, for the first time, that blocking a receptor of a key hormone in the renin-angiotensin system (RAS) reduces cancer cell growth by activating the enzyme AMPK to inhibit fatty acid synthase, the ingredients to support cell division. With that, a new chemopreventive agent that inhibits the …


Leukemia Drug Reverses Tamoxifen-Resistance in Breast Cancer Cells

Taking a leukemia chemotherapy drug may help breast cancer patients who don’t respond to tamoxifen overcome resistance to the widely-used drug, new research from the Kimmel Cancer Center at Jefferson suggests. Interestingly, researchers found that tamoxifen combined with dasatinib, a protein-tyrosine kinase inhibitor, reverses the chemo-resistance caused by cancer-associated fibroblasts in the surrounding tissue by …


Radiation after prostate removal is cost-effective, but less likely to be recommended by urologists

Receiving radiation therapy immediately after a radical prostatectomy is a cost-effective treatment for prostate cancer patients when compared with waiting and acting on elevated prostate-specific antigen (PSA) levels, according to a new study by researchers at Thomas Jefferson University and Hospital. What’s more, a separate, but related study, found that urologists were less likely than …


Director of KCC, Dr. Richard Pestell, in July issue of Runner’s World

Dr. Richard Pestell, director of the Kimmel Cancer Center at Jefferson and former national-class distance runner, was featured in the July issue of Runner’s World. Dr. Pestell spoke with the magazine for the cover story titled “Outrunning Cancer”–which focused on the running community’s ability to raise million of dollars each year to fight cancer. “When …


Bernadette E. Garofola Named ASRT Fellow

Bernadette E. Garofola, M.Ed., R.T.(R)(T)(CT), chief radiation therapist at Thomas Jefferson University Hospital, has been named a Fellow of the American Society of Radiologic Technologists. Ms. Garofola was honored at a ceremony on June 18 at the ASRT Annual Governance and House of Delegates Meeting in Albuquerque, N.M. The honorary Fellow category was established by …


Edith Mitchell Receives ‘Practitioner of the Year’ Award from Philadelphia County Medical Society

Edith Mitchell, M.D., clinical professor of Medicine and Medical Oncology at Jefferson Medical College of Thomas Jefferson University, was named 2011 “Practitioner of the Year” Award by the Philadelphia County Medical Society (PCMS). For her excellence in clinical care and community service, Dr. Mitchell will be presented the award on Saturday, June 11, during the …


KCC American Cancer Society Research Symposium

The 3rd Annual Kimmel Cancer Center American Cancer Society Research Symposium will be held today at 2 p.m. in 101 BLSB. KCC Director Richard Pestell, M.D, Ph.D, will present the keynote address and 2010 American Cancer Society-Institutional Research Grant Award recipients. Amy Leader, DrPH, MPH, and Hushan Yang, Ph.D, will discuss their research. A reception …


Dr. Pestell and the Thomas Jefferson University Hospital to be honored by the Susan G. Komen for the Cure

Dr. Richard Pestell, Director of the Kimmel Cancer Center at Jefferson, will receive the “Light of Life” award at the 2010 Susan G. Komen Pink Tie Ball on Saturday, October 16.  Also that evening the “Beacon of Hope” award to the Thomas Jefferson University Hospital  will be accepted by Thomas J. Lewis, President and CEO, …

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