Archives

13
Jun

Christine Eischen, PhD, Receives Prestigious Professorship in Cancer Research

Congratulations to Christine M. Eischen, PhD, who was recently invested as the Herbert A. Rosenthal, MD ’56 Professor in Cancer Research. Eischen is a professor and Vice Chair in the Department of Cancer Biology at Thomas Jefferson University and co-leader of the Molecular Biology & Genetics Program at the Sidney Kimmel Cancer Center at Jefferson …

5
Dec

Researchers Find Breakthroughs in Understanding Genetic Basis of Aggressive Prostate Cancer

The retinoblastoma (RB) susceptibility gene was the first gatekeeper gene discovered for cancer. When it was removed or damaged, cancer thrived. Over the years, researchers have discovered methods that have allowed them to experimentally remove the RB gene in order to study it, but just how the gene’s loss made cancers more aggressive was poorly understood. By studying patient samples, …

28
Nov

Decoding the Molecular Mechanisms of Ovarian Cancer Progression

A new study from Sidney Kimmel Cancer Center (SKCC) investigator Christine Eischen, PhD, provided important new insights into the mechanisms contributing to ovarian cancer. The findings were recently published in Nature Communications. Ovarian cancer is the most lethal gynecologic malignancy in the United States, resulting in an estimated 14,100 deaths and 22,500 new cases in 2017 …

18
Aug

Colorectal Cancer Metastasis: A Game of Clones

Colorectal cancer is highly prevalent worldwide, and metastasis of colorectal cancer to distant sites accounts for ~90% of the mortality associated with this disease. Researchers at the Sidney Kimmel Cancer Center at Jefferson (SKCC), along with collaborators at several other institutions, tracked genomic changes that occur as colorectal tumors progress and metastasize to distant sites …

25
Apr

New Insights into G Protein-Coupled Receptor Signaling and Regulation

A collaborative study by the laboratories of Jeffrey L. Benovic, PhD,  in the Department of Biochemistry and Molecular Biology at Thomas Jefferson University and the Sidney Kimmel Cancer Center at Jefferson, and Dr. Brian K. Kobilka in the Department of Molecular and Cellular Physiology at the Stanford University School of Medicine provides new insights into a …

25
Apr

You Can Help Save PA Research Funding

For more than a decade, Pennsylvania’s Commonwealth Universal Research Enhancement Program (CURE) has supported a broad range of biomedical research at 39 institutions across Pennsylvania. These funds have led to research advances in cancer, cardiovascular disease, diabetes, infectious diseases, and other health areas and improvements in public health. In his budget for fiscal year 2013, …

8
Nov

Kimmel Cancer Center Hosts Interurban Clinical Club

On Friday, October 28, the Kimmel Cancer Center at Jefferson hosted the 204th meeting of the Interurban Clinical Club at Jefferson Medical College of Thomas Jefferson University. The Interurban Clinical Club is a prestigious club founded by Sir William Osler in 1905 for the purpose of exchanging ideas and fellowship among medical teachers in some …