Decoding the Molecular Mechanisms of Ovarian Cancer Progression

A new study from Sidney Kimmel Cancer Center (SKCC) investigator Christine Eischen, PhD,┬áprovided important new insights into the mechanisms contributing to ovarian cancer. The findings were recently published in Nature Communications. Ovarian cancer is the most lethal gynecologic malignancy in the United States, resulting in an estimated 14,100 deaths and 22,500 new cases in 2017 …


Cancer Cell Signaling: Selecting the Best Importin for the Job

New research from Sidney Kimmel Cancer Center at Jefferson member Gino Cingolani, PhD,┬árecently provided critical insights into the nuclear import of key signaling proteins, including those involved in tumorigenesis. For a vast array of cellular processes, numerous proteins must be imported and exported from the cell nucleus in a tightly regulated fashion. Typically, proteins that …