American Association for Cancer Research Elects SKCC Director Karen Knudsen to Board of Directors

The members of the American Association for Cancer Research (AACR) have elected Karen E. Knudsen, PhD, Executive Vice President of Oncology Services and Enterprise Director of the Sidney Kimmel Cancer Center – Jefferson Health (SKCC) to its Board of Directors. Knudsen is one of five world-renowned cancer researchers elected to the board for the 2019-2022 …


SKCC Director Dr. Karen Knudsen Named Association of American Cancer Institutes’ President-Elect

Karen E. Knudsen, PhD, Enterprise Director of the National Cancer Institute (NCI)-designated Sidney Kimmel Cancer Center– Jefferson Health (SKCC), has been elected vice president/president-elect of the Association of American Cancer Institutes’ (AACI) board of directors. Dr. Knudsen, who has been serving as SKCC enterprise director since 2015, governs cancer research and cancer care across 14 hospitals within …


New Recommendations Provide Guidance on Genetic Counseling & Testing for Hereditary Prostate Cancer

To date, there have been few recommendations to guide physicians about when to offer men genetic consultation for prostate cancer risk. Now, an international and interspecialty panel of experts convened at the Sidney Kimmel Cancer Center (SKCC) at Jefferson have developed a comprehensive set of recommendations. This consensus statement, published December 13th in the Journal …


Researchers Find Breakthroughs in Understanding Genetic Basis of Aggressive Prostate Cancer

The retinoblastoma (RB) susceptibility gene was the first gatekeeper gene discovered for cancer. When it was removed or damaged, cancer thrived. Over the years, researchers have discovered methods that have allowed them to experimentally remove the RB gene in order to study it, but just how the gene’s loss made cancers more aggressive was poorly understood. By studying patient samples, …


Knudsen and Kelly Receive NCI Funding

Two Sidney Kimmel Cancer Center investigators, Karen Knudsen, PhD, and Wm. Kevin Kelly, DO, have been awarded a new R01 grant from the National Cancer Institute to develop more effective therapeutic strategies for advanced prostate cancer. The project builds on previous discoveries from these investigators that identified specific cell cycle alterations in metastatic castrate-resistant prostate cancer and …


Ayesha Shafi receives PCF Young Investigator Award

Ayesha Shafi, PhD, a postdoctoral researcher in the laboratory of Sidney Kimmel Cancer Center Director Dr. Karen Knudsen, has been awarded a prestigious Prostate Cancer Foundation (PCF) Young Investigator Award. Shafi is conducting research on the role of the androgen receptor and the DNA repair factor DNA-dependent protein kinase in prostate cancer. Her studies are …


Single-Cell Resolution Mutational Profiling in Breast Cancer

A new study from Sidney Kimmel Cancer Center at Jefferson demonstrated the feasibility of detecting cancer-associated gene mutations in circulating tumor cells (CTC) isolated from patients — providing a powerful new tool for clinicians and cancer researchers. Published in Clinical Cancer Research, the project was led by senior authors Paolo M. Fortina, MD, PhD, and Massimo …


Curry spice component may help slow prostate tumor growth

Curcumin, an active component of the Indian curry spice turmeric, may help slow down tumor growth in castration-resistant prostate cancer patients on androgen deprivation therapy (ADT), a study from researchers at Jefferson’s Kimmel Cancer Center suggests. Reporting in a recent issue of Cancer Research, Karen Knudsen, Ph.D., a Professor of Cancer Biology, Urology and Radiation …


Dr. Karen Knudsen Receives Ron Ross Award

See the Award Announcement for more information about the Award and its latest recipient. The following was abstracted from the announcement. Dr. Karen Knudsen of the Kimmel Cancer Center received the Ron Ross Award at the 5th Pacific Rim Breast and Prostate Cancer Meeting, held in Kingscliff, Australia, May 3-7, 2011. Dr. Ron Ross was …


Loss of the retinoblastoma tumor suppressor pushes prostate cancer into lethal stage, say Kimmel Cancer Center researchers

Their study, the first to uncover a new role for this powerful gene, may lead to clinical “barcoding” of a patient’s prostate cancer to help direct therapy (PHILADELPHIA) – The retinoblastoma tumor suppressor gene (Rb), long thought to protect cells against cancer development, appears to play a very different role in prostate cancer, say scientists …


Karen Knudsen receives Richard E. Weitzman Memorial Award

Karen Knudsen, PhD, Associate Professor, Department of Cancer Biology and Urology at the Kimmel Cancer Center received the Richard E. Weitzman Memorial Award from the Endocrine Society. This annual Laureate Awards annual award recognizes an exceptionally promising young clinical or basic investigator. Knudsen is recognized for scientific achievements in the study of androgen action in …


The Endocrine Society awards KCC scientist

The Endocrine Society is pleased to announce the 2009 Laureate Awards established in 1944 to recognize the highest achievements in endocrinology including: science, leadership, teaching and service. This year’s Laureate Awards were presented at ENDO 09, the 91st Annual Meeting of The Endocrine Society, being held June 10-13, in Washington, DC. Karen Knudsen, PhD, Associate …