A new study from Sidney Kimmel Cancer Center – Jefferson Health (SKCC) researchers provides important insights into the role of DNA replication fork remodeling in mitigating stress on DNA caused by dysregulation of the Myc oncogene, which occurs in at least 70 percent of human cancers. The study was published in the journal Cancer Research. …

Congratulations to Christine M. Eischen, PhD, who was recently invested as the Herbert A. Rosenthal, MD ’56 Professor in Cancer Research. Eischen is a professor and Vice Chair in the Department of Cancer Biology at Thomas Jefferson University and co-leader of the Molecular Biology & Genetics Program at the Sidney Kimmel Cancer Center at Jefferson …

A new study from Sidney Kimmel Cancer Center (SKCC) investigator Christine Eischen, PhD, provided important new insights into the mechanisms contributing to ovarian cancer. The findings were recently published in Nature Communications. Ovarian cancer is the most lethal gynecologic malignancy in the United States, resulting in an estimated 14,100 deaths and 22,500 new cases in 2017 …

Christine M. Eischen, PhD, Co-Leader of the Molecular Biology & Genetics Program at the Sidney Kimmel Cancer Center at Jefferson, has been awarded a 2017 AACR-Bayer Innovation and Discovery Grant. Her grant is entitled, “Using PROTACS to target the Mdm2 oncoprotein.” The Innovation and Discovery Grant offers one-year grants to “meritorious projects that examine important, and …

Investigators at the Sidney Kimmel Cancer Center at Jefferson uncovered potential new culprits that contribute to the development and progression of several types of lymphoma. The study was published in a recent issue of Clinical Cancer Research, with co-first authors Drs. Clare M. Adams and Ramkrishna Mitra, along with co-author Dr. Jerald Z. Gong and senior author Christine …

New research from the laboratory of Christine Eischen, PhD, Co-Leader of the Molecular Biology and Genetics Program at the Sidney Kimmel Cancer Center at Jefferson, has revealed a previously unappreciated feature of a well-known cell survival mechanism with potentially important implications for the treatment of some cancers. The study, recently published in Cancer Research, focuses on the …