23
Aug

Researchers Find New Clues to Treat Rare and Aggressive Inflammatory Breast Cancer

A study led by investigators from Thomas Jefferson University’s Kimmel Cancer Center has discovered molecular clues that may help physicians therapeutically target inflammatory breast cancer (IBC), a highly aggressive form of breast cancer. Their study, reported in the June 21 online issue of Breast Cancer Research and Treatment, identified two molecules (ALK and FAK1) involved in the …

23
Aug

Protein in Blood Exerts Natural Anti-Cancer Protection

Researchers from Thomas Jefferson University’s Kimmel Cancer Center have discovered that decorin, a naturally occurring protein that circulates in the blood, acts as a potent inhibitor of tumor growth modulating the tumor microenvironment. The study, published June 24 online in the Proceedings of the National Academy of Sciences (http://www.pnas.org/content/early/2013/06/19/1305732110.abstract), suggests it may be possible to …

23
Aug

Researchers Discover Molecule That Drives Aggressive Breast Cancer

Recent studies by researchers at Thomas Jefferson University’s Kimmel Cancer Center have shown a gene known to coordinate initial development of the eye (EYA1) is a powerful breast tumor promoter in mice. The gene EYA1 was also shown to be overexpressed in a genetic breast cancer subtype called luminal B. The scientists found that excess …

23
Aug

Need to Analyze Your Next-Generation Sequencing Data? Thomas Jefferson University’s New Web-Based Resource Makes the Task Easy

In the early 1990s, an international effort was launched by the U.S. Department of Energy and the National Institutes of Health to sequence the human genome. The project took 13 years, involved many scientists in several countries, and cost $2.7 billion (in FY 1991) dollars. Since then, technological advances and the advent of next generation sequencing …

23
Aug

Tool to Ensure Accuracy of Radiation Treatment Plan Will Improve Quality and Save Time for Cancer Patients

It is critical that a cancer treatment plan that uses radiation be checked, and checked again, before patients are exposed to the therapy. Radiation mistakes can reduce survival, increased toxicity, and result in poor tumor control. Evaluating the radiation treatment plan, however, can be time-consuming and labor-intensive, especially in large-scale multi-institutional clinical trials, say radiation physicists …

23
Aug

KCC Ranked as One of Best Cancer Hospitals in US

Men’s Health magazine recently ranked the Kimmel Cancer Center at Jefferson among the best in the nation, calling out its success in treating prostate cancer, a leading cancer in men. The American Cancer Society estimates there will be more than 1.5 million new cancer diagnoses in 2013. Jefferson scientist, Matthew Schiewer, Ph.D., recently received the Prostate Cancer Benjamin …

16
Jul

Dr. Iozzo’s recent PNAS publication shows link between decorin to autophagy in endothelial cells

Dr. Renato Iozzo, MD, PHD, Professor of Pathology & Cell Biology, Biochemistry & Molecular Biology and Kimmel Cancer Center member, and his group recently published results in the Proceedings of the National Academy of Science (PNAS) which show decorin functions as a tumor suppressor/anti-angiogenesis factor, in part, by inducing the autophagy of endothelial cells. The …

3
Jul

Keatley Foundation Donation

The Keatley Foundation made a generous $10,000 donation to the Kimmel Cancer Center.   Events like their second annual Beef and Beer contributed to this generous donation. The Keatley Foundation was created by Bob Lyons during his treatment at Jefferson Hospital. The foundation name comes from the street name where Bob lives. According to Bob, That …

18
Jun

KCC Investigator wins Prostate Cancer Foundation Benjamin Franklin Young Investigator Award

Matthew Schiewer, PhD, a postdoctoral fellow in Dr. Karen Knudsen’s lab in the Department of Cancer Biology, is the recent recipient of a Prostate Cancer Foundation Young Investigator Award. Dr. Schiewer’s investigations will focus on the role of PARP-1 in DNA damage repair and the inhibition of PARP with specific medications as a potential therapy …

17
Jun

2013 Kimmel Cancer Center Ball

On Saturday June 8th, 2013, the Kimmel Cancer Center held its 4th Ball at the Ritz Carlton Philadelphia. Edward Glickman, the Kimmel Cancer Center’s first Advisory Board Chairman was honored and presented with the “Spirit of Commitment” Award. Please look here for more details about the 2013 KCC Ball. A gallery from the Ball is …

13
May

Kimmel Cancer Center “All Hands” Meeting

The Kimmel Cancer Center held it’s quarterly “All Hands” meeting on May 1, 2013. Dr. Richard Pestell, Director of the Kimmel Cancer Center, delivered his quarterly “State of the Cancer Center” address. Awards were presented in four categories. A special “Lifetime Achievement” Award was presented to Jouni J. Uitto, MD. The Basic Science Award was …

8
May

Jefferson Post-Doc Receives National Cancer Center Fellowship

Edward Hartsough, Ph.D. received a post-doctoral fellowship from the National Cancer Center Organization ( http://www.nationalcancercenter.org/ ).  The fellowship grant is entitled “Next-Generation RAF Inhibitors in V600E BRAF Melanoma.”  Dr. Hartsough works in Dr. Andrew Aplin’s lab at the Kimmel Cancer Center. The National Cancer Center was founded by Dr. J. Ernest Ayre in 1953 as …

22
Mar

Team Jefferson at 2013 Get Your Rear in Gear Race

Supporters of the Kimmel Cancer Center joined “Team Jefferson” for this year’s Get Your Rear in Gear 5K and 10K runs, 2 mile walk or a kids’ fun run. Proceeds support cutting edge research in colorectal cancer and compassionate care. Maria Grasso, founder and organizer of GYRIG Philadelphia, presented a check to Jefferson from last …

22
Mar

Jefferson Graduate Student Receives 2013 Joanna M. Nicolay Melanoma Foundation Award

Curtis Kugel, a Thomas Jefferson University graduate student in the Department of Cancer Biology, was one of 10 students from leading cancer centers across the U.S. to receive a $10,000 “Research Scholar Award” (RSA) from the Joanna M. Nicolay Melanoma Foundation (JMNMF) for his exceptional research work. JMNMF Chair, Regina Shannon Bodnar, and Board/RSA Committee …

6
Mar

Remembering ASCO Founding Member Dr. Jane Cooke Wright

In February, the American Society of Clinical Oncology (ASCO) announced the passing of Jane Cooke Wright, M.D., a true pioneer, mentor, and renowned researcher. Dr. Wright was one of seven founding members of ASCO – the only woman among the founders – and the Society’s first Secretary/Treasurer. She died on Tuesday, February 19 at the …

14
Feb

2nd Annual Spring Fling

Please join us for our 2nd Annual Spring Fling benefiting the Helping Hand Fund for cancer patients and caregivers. Save The Date Announcement April 12, 2013 8:00 PM to MIDNIGHT The Waterfall Room 2015 S. Water Street, Philadelphia, PA 19148 Tickets $50.00 Includes buffet dinner, top-shelf open bar, dancing, raffles, 50/50 and door prizes Contact …

12
Feb

Massimo Cristofanilli, M.D., Appointed Director of the Jefferson Breast Care Center

Massimo Cristofanilli, M.D., FACP, an internationally renowned breast cancer researcher and clinician, has been appointed Director of the Jefferson Breast Care Center at the Kimmel Cancer Center (KCC) and Thomas Jefferson University and Hospitals. With more than 25 years of clinical, basic science and educational experience, Dr. Cristofanilli will also serve as Deputy Director of …

12
Feb

Jefferson Opens Calorie Restriction Trial for Early Stage Breast Cancer Patients on Radiation Therapy

Jefferson’s Kimmel Cancer Center will begin a first-of-its-kind clinical trial that uses calorie restriction to help treat early stage breast cancer patients undergoing radiation therapy. Evidence suggests that reducing patients’ calorie intake could help shrink tumors and improve survival because it enhances the effectiveness of radiation therapy, the team explains in a recent review published …

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