Three Hits to Fight Lung Cancer

In experimental models of lung cancer, researchers show that a combo of two drugs plus radiation could make a subset of treatment-resistant lung cancers susceptible to therapy. (PHILADELPHA) – Although the most common type of lung cancer – non-small cell lung cancer (NSCLC) – has recently seen major treatment advances in some genetic subtypes, other …


SKCC Member receives R21 Grant

Dr Isidore Rigoutsos, PhD Director of Computational Medicine Center: Cancer Biology, Pathology, Anatomy and Cell Biology for the Sidney Kimmel Cancer Center and Professor Biochemistry & Molecular Biology was recently awarded an R21 grant for the Discovery of Novel miRNAs and isomiRs and Use in Sub-typing TCGA cancers.  Summary Statement from Dr. Rigoutsos: Recently, we …


Atezolizumab Could Change Standard of Care in Metastatic Urothelial Cancers

“This primary analysis of IMvigor 210 demonstrated that atezolizumab has the potential to change the standard of care for metastatic urothelial cancers.” – Jean H. Hoffman-Censits, MD Second-line treatment with atezolizumab (MPDL3280A) resulted in a median overall survival (OS) of 11.4 months in patients with locally advanced or metastatic urothelial carcinoma (mUC) and who showcased …


SKCC Researcher Named one of 3 New Outrun the Sun Melanoma Research Scholars

  OUTRUN THE SUN NAMES THREE NEW MELANOMA RESEARCH SCHOLARS Jessica Teh, Post Doc Fellow – Dr. Andrew Aplin Lab Indianapolis: Outrun the Sun, Inc., (www.outrunthesun.org) a nonprofit organization supporting skin cancer education and melanoma research, welcomes three new melanoma researchers to the Outrun the Sun Melanoma Research Scholar Program. The 2015 Scholars are: Brian …


Saving Eyes, Saving Vision

A Neurosurgeon and an Oncologist Join Forces to Treat a Childhood Eye Cancer   IN 2011, LEANNE DAVIS, a new mom and high school English teacher from Warren, Mich., took her 4-month-old son Cole with her to her regular eye exam. As a child, Leanne had retinoblastoma, a rare and potentially deadly cancer of the …


Two SKCC PhD Students Invited To Present Research At International Meetings

Congratulations to two PhD students in Dr. Karen Knudsen’s laboratory who have been invited to speak at upcoming Keystone Symposia on Molecular and Cellular Biology!! Jennifer Jones McMann, a student in the Genetics, Genomics and Cancer Biology PhD Program, will present “Novel Action of p53 Gain-of-Function Mutation in Prostate Cancer Progression” at the Keystone Conference …


Dr. Robert Den featured on eCancerTV

Dr Den talks to ecancertv at ASTRO 2015 about a study that found a commercially available genomic classifier for prostate cancer may be able to help predict which men may benefit from additional systemic therapy after prostatectomy and salvage radiotherapy. In the interview he describes how the test was able to predict which men would …


New RO1 Award Announcement: Dr. Sue Menko

Sidney Kimmel Cancer Center Member Dr. Susan Menko, was recently award an NIH funded RO1 Grant In the grant “Repurposing Classical Death Pathways for Signaling Roles in Lens Differentiation” a Multiple PI team led by Sue Menko proposes to investigate normal signaling functions for classical apoptotic and autophagy pathways in the context of regulating crucial …


Palliative Care in Oncology Plan for PA

Margaret “Peg” O’Grady, Director of Nursing for the Department of Medical Oncology has been selected to work on a collaborative initiative of creating an oncology palliative care plan for the state of Pennsylvania. Her role at Jefferson had made her a critical stakeholder  positioned to advance oncology palliative care.  This initiative is being led by …


NIH Awards $350K for Study of Compound That Could ‘Starve’ Pancreatic Tumors

In the Curtis Building laboratories, Drs Jordan Winter, Jonathan Brody and Susan Lanza-Jacoby join forces to disrupt the energy supply of pancreatic cancer cells. Susan Lanza-Jacoby, PhD, has been awarded the National Institutes of Health Cancer Institute grant for her work with Jonathan Brody, PhD, Director of Surgical Research and Co-Director of the Jefferson Pancreas, …


PODCAST: Radiation Oncology Residency Program at TJU

                          Dr. Adam Dicker (Professor & Chairman)                          Dr. Voichita Bar Ad (Residency Program Director) On November 12th, 2015, the Department of Radiation Oncology, under the leadership of Dr. Adam P. Dicker and Dr. Voichita Bar Ad, recorded our first podcast with special focus …


Dr. Den Featured in ASCOPost: Genomic Test Identifies Patients With Prostate Cancer in Need of Intensified Salvage Therapy

Prostate cancer has been slow to catch up with breast cancer in terms of using biomarkers, but a new study represents progress in this regard. A genomic classifier called Decipher® provides important information that can be used to make treatment decisions for men with prostate cancer and a rising prostate-specific antigen (PSA) after radical prostatectomy. …

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