7
Jul

Jefferson Researchers Show Antibody to Breast Cancer- Secreted Protein Blocks Metastasis

Scientists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have made a key discovery about the mechanism of breast cancer metastasis, the process by which cancer spreads. Focusing on a gene dubbed “Dachshund,” or DACH1, they are beginning to pinpoint new therapeutic targets to halt the spread of cancer. Reporting their findings …

18
Jun

Blocking Signaling Protein Prevents Prostate Cancer Spread, Jefferson Scientists Find

Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia have shown that by blocking a signaling protein, they can prevent prostate cancer cells from metastatic dissemination. The work opens the door to future studies examining the protein as a target for therapies aimed at keeping prostate cancer at bay. In a series of experiments …

18
Jun

Jefferson, Ohio State Team Find Gene Signature Profile for Metastasis

A common signature of tiny, specific pieces of non-coding genetic material known as microRNAs (miRNAs) may be directly involved in the spread of cancer to other parts of the body. Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia and Ohio State University Medical Center in Columbus have identified such a signature, made up …

3
Jun

Monitoring Blood Flow Helps Improve Prostate Biopsies, Jefferson Researchers Report

Using a special ultrasound technique to spot areas of blood flow in the prostate gland may substantially reduce the number of unnecessary biopsies, according to a new study by urologists and radiologists at the Jefferson Prostate Diagnostic Center and the Kimmel Cancer Center at Jefferson in Philadelphia. The researchers found that biopsies targeted to areas …

23
May

Traditional Herbal Medicine Kills Pancreatic Cancer Cells, Kimmel Cancer Center at Jefferson Researchers Report

An herb used in traditional medicine by many Middle Eastern countries may help in the fight against pancreatic cancer, one of the most difficult cancers to treat. Researchers at the Kimmel Cancer at Jefferson in Philadelphia have found that thymoquinone, an extract of Nigella sativa seed oil, blocked pancreatic cancer cell growth and killed the …

14
Apr

Jefferson Scientists’ Discovery May Help Explain Smoking-Pancreatic Cancer Link

If lung cancer and heart disease aren’t bad enough, cigarette smokers are also at higher risk for developing, among other things, pancreatic cancer. Now, researchers at the Kimmel Cancer at Jefferson in Philadelphia have preliminary evidence indicating one possible reason why. Data being presented April 13, 2008 during the Annual Meeting of the American Association …

14
Apr

Neal Flomenberg, M.D., Named Chair of the Department of Medical Oncology at Jefferson

Bone marrow transplant expert Neal Flomenberg, M.D., has been named the new chair of the Department of Medical Oncology at Jefferson Medical College of Thomas Jefferson University, Thomas Jefferson University Hospital and the Kimmel Cancer Center at Jefferson in Philadelphia. Dr. Flomenberg, who is also Clinical Deputy Director at the Kimmel Cancer Center and professor …

14
Apr

Blood Pressure Drugs Halt Pancreatic Cancer Cell Growth, Jefferson Researchers Find

Researchers at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia are inching closer to understanding how common blood pressure medications might help prevent the spread of pancreatic cancer. They have found in the laboratory that one type of pressure-lowering drug called an angiotensin receptor blocker inhibits pancreatic cancer cell growth and causes cell …

3
Apr

Jefferson, PanCAN Holding Program April 5 to Help Patients, Families, and Public Learn More About Pancreatic Cancer

The message about pancreatic cancer is changing, says renowned surgeon Charles J. Yeo, M.D. New imaging techniques, improved early detection and screening of high-risk groups, and new therapies on the horizon have begun to change the way pancreatic cancer is viewed. “There’s been a shift in the way we treat and think about this disease,” …

1
Apr

Kimmel Cancer Center Hosts Program to Help Patients and Families Learn More About Living with Cancer April 2

The Kimmel Cancer Center at Jefferson in Philadelphia is holding a program on Wednesday, April 2, 2008 for patients, families and caregivers whose lives have been touched by cancer. “Life After A Cancer Diagnosis” will feature speakers addressing topics ranging from exercise and cancer fatigue to caregiver issues to questions about fertility and sexuality after …

31
Mar

Kimmel Cancer Center Scientist Named Editor-in-Chief of Prestigious Pathology Journal

Renowned cell biologist Michael P. Lisanti, M.D., Ph.D., the Margaret Q. Landenberger Professor in Breast Cancer Research at Jefferson Medical College of Thomas Jefferson University and the Kimmel Cancer Center at Jefferson in Philadelphia, has been named Editor-in-Chief of The American Journal of Pathology (AJP). His term begins in July. Dr. Lisanti, who serves as …

17
Mar

Jefferson Establishes New Center to Study Stem Cells and Regenerative Medicine

Thomas Jefferson University has established a new center to study the biology, behavior and the potential medical uses of adult stem cells in a variety of diseases, including neurological disease and cancer. The Jefferson Stem Cell Biology and Regenerative Medicine Center will be directed by renowned cell biologist Michael P. Lisanti, M.D., Ph.D., professor of …

29
Feb

Blocking Growth Protein Kills Prostate Cancer Cells, Inhibits Tumor Growth, Jefferson Scientists Find

Researchers at Jefferson’s Kimmel Cancer Center in Philadelphia have shown that they can effectively kill prostate cancer cells in both the laboratory and in experimental animal models by blocking a signaling protein that is key to the cancer’s growth. The work proves that the protein, Stat5, is both vital to prostate cancer cell maintenance and …

27
Feb

New Jefferson Trial to Test Radiation-Emitting Beads Against Advanced Liver Cancer

Liver cancer specialists at Jefferson’s Kimmel Cancer Center in Philadelphia are beginning an 18-month study of a new treatment for liver cancer. The therapy entails injecting tiny beads that emit small amounts of radiation into the liver’s main artery while also blocking the blood supply feeding the cancer’s growth. The technique, called radioembolization, has been …

27
Feb

Kimmel Cancer Center Faculty Elected as Secretary of the Association of Cancer Executives (ACE)

Joy Soleiman, MPA, Clinical Administrator of the Kimmel Cancer Center, was elected to a two year term as Secretary of the Association of Cancer Executives (ACE). It was officially announced at their annual meeting in San Francisco February 16 to 19, 2008. ACE is a leading cancer administrator networking organization for over a decade with …

27
Feb

Jefferson Scientists Uncover Role of Cancer Stem Cell Marker: Controlling Gene Expression Patterns

Scientists at Jefferson’s Kimmel Cancer Center in Philadelphia have made an extraordinary advance in the understanding of the function of a gene previously shown to be part of an 11-gene “signature” that can predict which tumors will be aggressive and likely to spread. The gene, USP22, encodes an enzyme that appears to be crucial for …

21
Jan

Jefferson Scientists Find Protein Helps Pancreatic Cancer Cells Hide from Immune System, Allowing Spread

A protein that helps prevent a woman’s body from rejecting a fetus may also play an important role in enabling pancreatic cancer cells to evade detection by the immune system, allowing them to spread in the body. Researchers at Jefferson’s Kimmel Cancer Center in Philadelphia found that the metastatic cancer cells in the lymph nodes …

3
Jan

Jefferson Scientists Find Cell Growth Protein Potential Drug Target for Treatment-Resistant Prostate Cancer

Scientists at Jefferson’s Kimmel Cancer Center in Philadelphia have found that a signaling protein that is key to prostate cancer cell growth is turned on in nearly all recurrent prostate cancers that are resistant to hormone therapy. If the findings hold up, the protein, called Stat5, may be a specific drug target against an extremely …

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