16
Apr

New Therapeutic Target for Melanoma Identified

A protein called Mcl-1 plays a critical role in melanoma cell resistance to a form of apoptosis called anoikis, according to research published this week in Molecular Cancer Research. The presence of Mcl-1 causes cell resistance to anoikis. This resistance to anoikis enables the melanoma cells to metastasize and survive at sites distant from the …

14
Apr

Jefferson’s Kimmel Cancer Center Researchers Receive $6.7 million Grant from Susan G. Komen for the Cure

Researchers from the Kimmel Cancer Center at Jefferson were awarded a Susan G. Komen for the Cure Promise Grant of almost $6.7 million for five years for continued breast cancer research. The project represents a multidisciplinary team of scientists from a consortium that also includes Walter Reed Army Medical Center and DecisionQ Inc. in Washington …

9
Apr

Cancer Programs Celebrate National Cancer Registrars Week,
April 13-17

Theme of “Cancer Registrars….Rock Solid” Emphasizes the Foundation Cancer Registrars Provide for Cancer Research, Awareness, Prevention and Quality Improvement Cancer registrars around the world will join their colleagues and local community leaders to observe the annual National Cancer Registrars Week, April 13–17, 2009. The 2009 theme “Cancer Registrars…Rock Solid” reflects the dependable professionalism cancer registrars …

26
Mar

Jefferson Kimmel Cancer Center Administrator Appointed President-elect of Association of Cancer Executives

Joy Soleiman, MPA, the Clinical Administrator for the Kimmel Cancer Center at Jefferson, has been appointed president-elect of the Association of Cancer Executives. The one-year appointment began in February at the association’s annual meeting. Ms. Soleiman will become president at the association’s annual meeting in 2010, to be held in San Diego. That is also …

24
Mar

Jefferson Breast Cancer Researcher to Receive PA Income Tax Check-Off Grant

Hallgeir Rui, M.D., Ph.D, a professor of Cancer Biology at Jefferson Medical College of Thomas Jefferson University and Jefferson’s Kimmel Cancer Center, is one of three recipients of the Income Tax Check-Off for Breast & Cervical Cancer Research grants this year. The $50,000 award will be used to conduct research to understand what causes the …

11
Mar

Proepithelin Encourages Cell Growth and Migration in Prostate Cancer

Researchers from Thomas Jefferson University have identified a protein that appears to play a significant role in the growth and migration of prostate cancer cells, especially androgen-independent prostate cancer cells. The study was published in the American Journal of Pathology. They also found that prostate cancer cells express more of the protein when compared to …

26
Jan

Pre-emptive Treatment Helped Curtail Skin Toxicity with Panitumumab

With a pre-emptive, prophylactic skin regimen, patients who receive panitumumab for treatment of metastatic colorectal cancer may be able to avoid some of the skin-associated toxicities, according to data presented at the 2009 American Society of Clinical Oncology Gastrointestinal Cancers Symposium in San Francisco. Edith Mitchell, M.D., a clinical professor in the Department of Medical …

26
Jan

Jefferson Scientists Discover a Key Protein Regulator of Inflammation and Cell Death

Reporting in the journal Nature, researchers led by Emad Alnemri, Ph.D., professor of Biochemistry and Molecular Biology in the Kimmel Cancer Center at Jefferson, discovered a key protein component involved in inflammation. The protein, AIM2 (absent in melanoma 2), is involved in the detection and reaction to dangerous cytoplasmic DNA that is produced by infection …

26
Jan

African-Americans Have Worse Prognosis Compared to Caucasians When Diagnosed With Colorectal Cancer

African-American patients with colorectal were more likely to present with worse pathological features at diagnosis and to have a worse five-year survival rate compared to Caucasian patients, according to a study conducted by researchers at Thomas Jefferson University. The results are being presented at the 2009 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium. …

5
Dec

A Place for Me

The Kimmel Cancer Center at Jefferson hosted “A Place for Me” in Bluemle Life Science Building on Saturday, November 10, 2007. A family program, “A Place for Me” supports and educates children whose parents or grandparents have cancer. The November program featured art, games, and storytelling to help children understand the disease process, and to …

19
Nov

Navigating the New Normal

Cartoon Boot Camp Tongue cancer survivor Christian “Patch” Patchell lead a “Cartoon Boot Camp” for young adult survivors on October 25, 2008. This innovative program, held in Hamilton Building, focused on using art as a tool to manage difficult feelings associated with cancer treatment and survivorship. A graphic artist and art instructor at University of …

6
Nov

Dr. Edith Mitchell Receives ‘Tree of Life’ Award

Edith P. Mitchell, M.D., clinical professor, Department of Medical Oncology at Jefferson Medical College of Thomas Jefferson University and associate director of Diversity Programs for the Kimmel Cancer Center at Jefferson, was recently honored with a ‘Tree of Life’ award from The Wellness of You, a local nonprofit health education and resource organization. The ‘Tree …

24
Oct

Nobel Laureate Barry Marshall to Receive the Lennox K. Black International Prize for Excellence in Biomedical Research

Two-day Symposium at Jefferson Will Focus on Transformational Discoveries in Cancer Research Barry Marshall, A.C., an Australian physician and researcher, was convinced that stomach ulcers developed from a bacterial infection and not from stress as commonly believed. In 1984, when working at the Royal Perth Hospital, he tested his theory on himself by drinking a …

24
Sep

Dr. Baserga presents latest findings at the 7th International Symposium on Translational Research in Oncology

Translational scientists from around the globe will assemble in Huntington Beach this October for the 7th International Symposium on Translational Research in Oncology. The program, developed by co-chairs Dennis J. Slamon M.D., Ph.D., and John Crown M.D., M.P.H., includes discussions on the latest translational research developments, to improve the clinical outcomes for cancer patients.

7
Jul

Jefferson Researchers Show Antibody to Breast Cancer- Secreted Protein Blocks Metastasis

Scientists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have made a key discovery about the mechanism of breast cancer metastasis, the process by which cancer spreads. Focusing on a gene dubbed “Dachshund,” or DACH1, they are beginning to pinpoint new therapeutic targets to halt the spread of cancer. Reporting their findings …

18
Jun

Blocking Signaling Protein Prevents Prostate Cancer Spread, Jefferson Scientists Find

Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia have shown that by blocking a signaling protein, they can prevent prostate cancer cells from metastatic dissemination. The work opens the door to future studies examining the protein as a target for therapies aimed at keeping prostate cancer at bay. In a series of experiments …

18
Jun

Jefferson, Ohio State Team Find Gene Signature Profile for Metastasis

A common signature of tiny, specific pieces of non-coding genetic material known as microRNAs (miRNAs) may be directly involved in the spread of cancer to other parts of the body. Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia and Ohio State University Medical Center in Columbus have identified such a signature, made up …

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