Jefferson Breast Cancer Researcher Named Margaret Q. Landenberger Professor


Nicole Simone HeadshotNicole Simone, MD, has been named the Margaret Q. Landenberger Professor. The professorship, which focuses on breast cancer research, was established in 2006 by the Margaret Q. Landenberger Research Foundation. Dr. Simone will be the second holder of the professorship.

“Dr. Simone is a cancer research pioneer who has dedicated her entire career to discovering forward-thinking methods of improving outcomes for cancer patients,” said Karen Knudsen, PhD, Director of the Sidney Kimmel Cancer Center (SKCC). “We are incredibly grateful for the Landenberger Foundation’s continued support of cancer research at Jefferson, which will help Dr. Simone and SKCC to fulfill our mission of advancing cancer research and comprehensive cancer care until every cancer is cured.”

“The Landenberger Foundation tries to be a springboard for science, providing seed funding for novel research and bright scientists in the hope our support gets their work to the next level,” said William R. Levy, President of Brown Brothers Harriman Trust Company of Delaware, N.A., which is the corporate trustee of the Margaret Q. Landenberger Research Foundation. “The Foundation is very proud to support Dr. Simone and the Sidney Kimmel Cancer Center in their continued fight against this devastating disease.”

Dr. Simone serves as Director of Jefferson’s Breast Radiation Oncology Center. She treats breast cancer patients with radiation while leading a research team, which enables her to take discoveries from the lab directly to patients in the clinic, using advances in radiation oncology to minimize side effects while optimizing cancer treatment. She has studied the long-term toxicity of radiation in breast cancer and is exploring new ways to target the cancer while protecting the heart and lungs.

Most recently, her research yielded promising evidence that decreasing caloric intake can make chemotherapy and radiation therapy more effective for early stage breast cancer patients and can decrease metastatic disease.

“I am humbled and honored by the generosity of donors like the Landenberger Foundation, who help make the work that we do at SKCC possible,” said Dr. Simone. “I feel fortunate to be able to allow patients to realize the potential benefits of new cancer therapies and I look forward to making new discoveries to benefit our patients for years to come.”