Category Philadelphia

21
Nov

Cancer Cell Signaling: Selecting the Best Importin for the Job

New research from Sidney Kimmel Cancer Center at Jefferson member Gino Cingolani, PhD, recently provided critical insights into the nuclear import of key signaling proteins, including those involved in tumorigenesis. For a vast array of cellular processes, numerous proteins must be imported and exported from the cell nucleus in a tightly regulated fashion. Typically, proteins that …

20
Nov

CyberKnife Provides Long-term Disease Control for Prostate Cancer Patients

Jefferson now offers treatment with the CyberKnife® System, a noninvasive alternative to surgery for treating cancerous and noncancerous tumors, which has been shown to provide excellent long-term results for patients with low-and intermediate-risk prostate cancer. According to a recent national 17-center study, after 10 years 98.4 percent of the 230 men monitored with low-risk prostate cancer who were treated with the …

17
Nov

Christine Eischen Receives 2017 AACR-Bayer Innovation and Discovery Grant

Christine M. Eischen, PhD, Co-Leader of the Molecular Biology & Genetics Program at the Sidney Kimmel Cancer Center at Jefferson, has been awarded a 2017 AACR-Bayer Innovation and Discovery Grant. Her grant is entitled, “Using PROTACS to target the Mdm2 oncoprotein.” The Innovation and Discovery Grant offers one-year grants to “meritorious projects that examine important, and …

7
Nov

Sidney Kimmel Cancer Center Grand Rounds Lecture: Elizabeth A. Platz

The Sidney Kimmel Cancer Center at Jefferson is pleased to welcome Elizabeth A. Platz, ScD, MPH, as this week’s lecturer in our Grand Rounds Series. Her talk is entitled “Population Science: Collaborating to Uncover Cancer Etiology While Reflecting on Translation to Reduce Cancer Burden.” Dr. Platz is a Professor, Martin D. Abeloff, MD Scholar in …

19
Oct

Knudsen and Kelly Receive NCI Funding

Two Sidney Kimmel Cancer Center investigators, Karen Knudsen, PhD, and Wm. Kevin Kelly, DO, have been awarded a new R01 grant from the National Cancer Institute to develop more effective therapeutic strategies for advanced prostate cancer. The project builds on previous discoveries from these investigators that identified specific cell cycle alterations in metastatic castrate-resistant prostate cancer and …

13
Oct

Ayesha Shafi receives PCF Young Investigator Award

Ayesha Shafi, PhD, a postdoctoral researcher in the laboratory of Sidney Kimmel Cancer Center Director Dr. Karen Knudsen, has been awarded a prestigious Prostate Cancer Foundation (PCF) Young Investigator Award. Shafi is conducting research on the role of the androgen receptor and the DNA repair factor DNA-dependent protein kinase in prostate cancer. Her studies are …

13
Oct

Elda Grabocka Recipient of V Foundation Scholar Research Award

Congratulations to Elda Grabocka, PhD, who has been given a prestigious V Foundation Scholar Research Award. Her grant, entitled “Targeting Stress Adaptive Mechanisms as a Strategy for Precision Oncology in Pancreatic Cancer,” is focused on investigating stress granules as predictors of drug resistance and as effective therapeutic targets for the treatment of KRAS-driven pancreatic cancer. …

19
Sep

Molecular Profiling of Key Survival Proteins in B-cell Lymphoma Subtypes

Investigators at the Sidney Kimmel Cancer Center at Jefferson uncovered potential new culprits that contribute to the development and progression of several types of lymphoma. The study was published in a recent issue of Clinical Cancer Research, with co-first authors Drs. Clare M. Adams and Ramkrishna Mitra, along with co-author Dr. Jerald Z. Gong and senior author Christine …

18
Aug

Colorectal Cancer Metastasis: A Game of Clones

Colorectal cancer is highly prevalent worldwide, and metastasis of colorectal cancer to distant sites accounts for ~90% of the mortality associated with this disease. Researchers at the Sidney Kimmel Cancer Center at Jefferson (SKCC), along with collaborators at several other institutions, tracked genomic changes that occur as colorectal tumors progress and metastasize to distant sites …

9
Aug

Thomas Jefferson University Hospital (Sidney Kimmel Cancer Center at Jefferson) Ranked No. 20 in the Nation for Cancer

Thomas Jefferson University Hospital (Sidney Kimmel Cancer Center at Jefferson) has been nationally ranked No. 20 in the cancer specialty for 2017-2018 by U.S. News & World Report. U.S. News & World Report Best Hospitals rankings recognize hospitals that treat the most challenging patients and evaluate each hospital’s use of advanced technologies, safety, outcomes, and …

4
Aug

Researchers Developing Strategy to Optimize Personalized Therapy for Pancreatic Cancer

New research from investigators at the Sidney Kimmel Cancer Center at Jefferson provides insight into a cellular mechanism underlying the ability of pancreatic cancer cells to resist a promising, personalized therapy. The study was recently published online in Cancer Research. The research team studied the role of an RNA-binding protein termed HuR in influencing the …

2
Aug

Abington – Jefferson Health Recognized by NRG Oncology

Congratulations to Abington – Jefferson Health, who was recently announced as the #3 top accruing Main Member site for Fiscal Year 2017 by NRG Oncology. The announcement was made at the NRG Oncology Semiannual Meeting, held July 13-15, 2017 in Philadelphia. NRG Oncology seeks to improve the lives of patients with cancer by conducting practice-changing …

14
Jul

A Lifelong Dedication to Cancer

When Alison Petok was five years old, her Nana died of leukemia. “If she had been diagnosed a decade or two later, perhaps she would have survived due to the advances in blood cancer research,” Alison reflected. Years later in 2017, Alison was nominated as “Woman of the Year” by The Leukemia & Lymphoma Society …

4
May

Kathleen O’Doherty Joins SKCC In Joint Navigator Position

We are excited to announce that Kathleen O’Doherty, RN, BSN, OCN, has joined us in the role of Nursing Care Coordinator: Oncology Outreach, a joint navigator position between Main Line Health Cancer Care and The Sidney Kimmel Cancer Center at Jefferson. Kathleen will work closely with physicians and members of the multidisciplinary care teams at both institutions …

28
Apr

Opening Up Chromatin for Cell Differentiation

Two new studies from the laboratory of Alex Mazo, PhD, at the Sidney Kimmel Cancer Center, along with collaborators from SKCC, the Vickie and Jack Farber Institute for Neuroscience at Thomas Jefferson University, and other institutions, provide new insights into the structure of chromatin and its implications for cellular differentiation.  The new work, appearing in …

25
Apr

New Insights into G Protein-Coupled Receptor Signaling and Regulation

A collaborative study by the laboratories of Jeffrey L. Benovic, PhD,  in the Department of Biochemistry and Molecular Biology at Thomas Jefferson University and the Sidney Kimmel Cancer Center at Jefferson, and Dr. Brian K. Kobilka in the Department of Molecular and Cellular Physiology at the Stanford University School of Medicine provides new insights into a …

30
Mar

2017 Ocular Melanoma Foundation–AACR Fellowship Awarded to Vivian Chua

The Sidney Kimmel Cancer Center at Jefferson is pleased to announce that Vivian Chua, PhD, has been awarded a 2017 Ocular Melanoma Foundation–American Associate for Cancer Research (AACR) Fellowship for her project, “Novel Epigenetic Targeting Approaches in Uveal Melanoma.” This one-year, $50,000 grant recognizes the significant impact of Dr. Chua’s research, its relevance to the …

29
Mar

Christine Bonaccorso Named Administrative Director of Sidney Kimmel Cancer Network

Please join us in congratulating Christine Bonaccorso, RN, BSN, OCN, on assuming the position of Administrative Director of the Sidney Kimmel Cancer Network. Over the past several months, Bonaccorso has proven to be an outstanding leader while serving as Interim Director, playing a critical role in several projects that have greatly enhanced the Cancer Network. …

24
Mar

Noelle Williams Inducted into Gold Humanism Honor Society

The Sidney Kimmel Cancer Center at Jefferson would like to congratulate Noelle L. Williams, MD, who has been selected for induction into the Gold Humanism Honor Society Resident Chapter of Thomas Jefferson University. The Gold Humanism Honor Society recognizes students, residents, and faculty who are exemplars of compassionate patient care and who serve as role …

21
Mar

Unite for HER Wellness Day – April 2, 2017

  The Sidney Kimmel Cancer Center at Jefferson encourages Jefferson Hospital System breast cancer patients to participate in the upcoming “Unite for HER Wellness Day” event to be held on Sunday, April 2, 2017. This event will allow breast cancer patients to meet in a small group setting with trained professionals to learn about complementary …

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