Category Leukemia


The Perfect Match Might Be the Imperfect One

When it comes to treating blood cancers like leukemia and lymphomas, new research shows that a half-matched donor bone marrow transplant may be just as good as a full match, in the first apples to apples type comparison of its kind. (PHILADELPHIA) – Bone marrow transplantation is a life-saving therapy for many patients with blood …


Dawn Scardino named 2012 LLS Woman of the Year

Dawn Scardino, Coordinator of Academic Services in the Department of Medical Oncology, was named the 2012 Leukemia & Lymphoma Society’s Woman of the Year for the eastern Pennsylvania Chapter. Dawn took the top recognition for raising almost $27,000 in a 10-week fundraising “race” that began on Jan. 30 and ended on April 12.  Four women …


Kimmel Cancer Center at Jefferson Celebrates 20 Years of Patient Care and Cancer Discovery

From October forward, the Kimmel Cancer Center at Jefferson (KCC), a National Cancer Institute-designated cancer center, is celebrating 20 years of service to the community and the groundbreaking cancer research from the scientists and physicians who’ve provided an invaluable contribution to medical science and healthcare. “This is truly a milestone for the Kimmel Cancer Center—it’s …


New Half-Match Bone Marrow Transplant Procedure Featured in Philadelphia Inquirer

Neal Flomenberg, M.D., chair of the Department of Medical Oncology at Jefferson and Dolores Grosso, DNP, co-principal investigator of the study, have developed a way to make stem-cell transplants work, even when only half the immune markers are matched. Featured in the “Check Up” section of The Philadelphia Inquirer, this research has major implications. Half-match transplants would triple …


Half-Match Bone Marrow Transplant Procedure Yields Promising Outcomes for Cancer Patients

Half-matched bone marrow or stem cell transplants for blood cancer patients have typically been associated with disappointing clinical outcomes. However, a clinical trial conducted at the Kimmel Cancer Center at Jefferson testing its unique, two-step half-match procedure has produced some promising results: the probability of overall survival was 45 percent in all patients after three years …


Therapeutic Effect of Imatinib Improved with Addition of Chloroquine

The therapeutic effects of the blockbuster leukemia drug imatinib may be enhanced when given along with a drug that inhibits a cell process called autophagy, researchers from the Kimmel Cancer Center at Jefferson reported in the Journal of Clinical Investigation. The cell-death effect of imatinib (Gleevec) was potentiated when chloroquine, an autophagy inhibitor, was given …