Dr. Andrew Aplin Receives New NIH/NCI R01 Grant Award

Dr. Andrew Aplin

Dr. Andrew Aplin

Congratulations to Dr. Andrew Aplin for receiving a federally award (National Institute of Health/National Cancer Institute) R01 grant for his project: Mutant BRAF-regulated transcription factors in melanoma progression.




Dr. Joshua Palmer Awarded 2015 ACRO Travel Award & CCF Oncology Trainee Travel Award

Joshua Palmer. MD

Joshua Palmer. MD

The American College of Radiation Oncology (ACRO) is pleased recognize Joshua Palmer, MD, resident of the Department of Radiation Oncology, Sidney Kimmel Medical College of Thomas Jefferson University for his essay on Financial Toxicity and offer him a Travel Award to attend ACRO’s 2015 Annual Meeting, to be held May 14- 16 in Arlington, Virginia.

For more about the ACRO Resident program see their website

The Conquer Cancer Foundation (CCF) of ASCO is pleased to announce that Dr. Joshua Palmer has been selected to receive a 2015 Oncology Trainee Travel Award. This awards program is part of our ongoing effort to support the continuing education and professional development of trainee oncologists. With this award Dr. Palmer will be able to attend the 2015 ASCO conference in Chicago, Il.

For more about the ACRO Resident program see their website




SKCC Students and Fellows Receive The 2015 AACR Woman In Cancer Research Scholar Awards

2015 SKCC AACR WIR Scholars

Ileine Sanchez, Dr. Jessica Teh, Dr. Mizue Terai, Arpita Mondal and Kristina Shahriari


The Women in Cancer Research (WICR) Council has selected Ileine Sanchez, BS and Jessica Teh, PhD, MizueTerai, PhD, Arpita Mondal and Kristina Shahriari as recipients of a 2015 WICR Scholar Award. The American Association for Cancer Research were especially pleased to be able to recognize Thomas Jefferson University’s Ileine Sanchez’s, Dr. Jessica Teh’s and Dr. Misue Trai’s outstanding abstracts in the field of melanoma and skin cancer research. The Lankeanu Institute of Medical Research’s Arpita Mondal’s abstract is entitled “A novel pro-angiogenic role for IDO1 in inflammatory tumor promotion”.  Drexel University School of Medicine’s Kristina Shahriari’s abstract is entiteld “Interleukin-1β secreted into the bone metastatic niche by androgen receptor-negative prostate cancer cells enables skeletal metastasis”.

WICR Scholar Awards are given annually to WICR members who are scientists-in-training and presenters of meritorious scientific papers at the AACR Annual Meeting. Selection is made based on the Program Committee’s rating of your proffered paper and recommendations from the WICR Scholar Award Selection Committee.

For more about other 2015 AACR Women In Cancer Research Scholar Awards see their website



Sidney Kimmel Cancer Center Recognized by Commission on Cancer (American College of Surgeons)

75 CANCER PROGRAMS EARN THE OUTSTANDING ACHIEVEMENT AWARD

The Commission on Cancer (CoC), a Quality Program of the American College of Surgeons, has presented the 2014 Outstanding Achievement Award (OAA) to 75 CoC-accredited cancer programs in the U.S.
This year the Sidney Kimmel Cancer Center has received this achievement.

Established in 2004, the OAA recognizes cancer programs that demonstrate excellence by earning commendation for all applicable standards and providing quality care to patients with cancer. A program earns the OAA by completing the accreditation survey and receiving a Performance Report that indicates an accreditation award of “Three-Year with Commendation” outlining the commendation ratings for the seven commendation-level standards and no deficiencies.

Currently, there are seven commendation standards:

* Standard 1.9 – Clinical Trial Accrual
* Standard 1.11 – Cancer Registrar Education
* Standard 1.12 – Public Reporting of Outcomes
* Standard 2.1 – College of American Pathologists (CAP) Protocols
* Standard 2.2 – Nursing Care
* Standard 5.2 – Rapid Quality Reporting System (RQRS) Participation
* Standard 5.6 – Accuracy of Data

These 75 programs received the OAA as a result of surveys performed in 2014, and represent approximately 15 percent of cancer programs surveyed during this period. The majority of recipients are community-based facilities; however, there are also academic hospitals, integrated networks, and a Veterans Affairs facility that also received this year’s award. New programs undergoing initial survey and National Cancer Institute (NCI)-designated programs are not eligible to earn the OAA.



Dr. Paul Stauffer Recognized By The Society of Thermal Medicine

Dr. Paul Stauffer

Dr. Paul Stauffer

Paul Stauffer, MD, Director of Thermal Oncology and Professor of Radiation Oncology, Sidney Kimmel Medical College of Thomas Jefferson University and has been named the recipient of the George Hahn Award at upcoming Society of Thermal Medicine Meeting meeting. The George M. Hahn Award is presented every other year to an investigator whose research has contributed in a significant way to new clinical applications in thermal therapy. This lecture is named in honor of Dr. George Hahn who received the first Robinson Award in 1989. Dr. Hahn led a highly productive clinical program grant at Stanford for many years and his fundamental work in the heat shock response and in how hyperthermia modifies chemotherapy sensitivity still stands today as foundational work. His highly productive career exemplifies the translational attributes of this award.

For more about the Society of Thermal Medicine set their website




DOD Grant Awarded To Drs. Zeigler-Johnson and Amy Leader

PhD and Amy Leader, PhD

Charnita Zeigler-Johnson, PhD and Amy Leader, PhD

Charnita Zeigler-Johnson, PhD, Assistant Professor of Medical Onoclogy and Amy Leader, PhD, Assistant Professor of Medical Oncology have been awarded a DOD Synergistic Award to support a project called, “A neighborhood-based intervention to reduce prostate cancer disparities.” This grant is a 3-year award. Dr. Ziegler Johnson will be serving as s the PI, and Dr. Leader is a Co-PI, along with Dr. Karen Glanz, a Co-PI at U Penn. This project will address an important issue in the catchment area and links to another NCI cancer center. Dr. Zeigler-Johnson and Leader are both members of the Division of Population Science in the Department of Medical Oncology.




Two Drexel University College of Medicine Professors Receive Grants Through Statewide Refunds for Breast Cancer Research Campaign

Pat Haipin-Murphy, President  & Founder, PA Breast Cancer Coalition; Mauricio Rcginalo, PhD, Associate Professor; Alessandro Fatatis, MD, PhD, Professor; and Kenny Simansky, PhD, Vice

Pat Haipin-Murphy, President & Founder, PA
Breast Cancer Coalition; Mauricio Rcginalo, PhD,
Associate Professor; Alessandro Fatatis, MD, PhD,
Professor; and Kenny Simansky, PhD, Vice Dean for
Research

The Pennsylvania Breast Cancer Coalition recently awarded two Drexel University College of Medicine researchers (and Sidney Kimmel Cancer Center Members) grants from its statewide Refunds for Breast Cancer Research campaign. Alessandro Fatatis, MD, PhD, professor in the Departments of Pharmacology & Physiology and Pathology & Laboratory Medicine, and Mauricio Reginato, PhD, associate professor in the Department of Biochemistry & Molecular Biology, each received a $50,000 award for their breast cancer research.

PBCC is honoring Reginato for his research in triple negative breast cancer. “My sister-in-law died from breast cancer at age 37 leaving behind two small children,” said Reginato. “As cancer researchers, these are the stories we want to eliminate. This program not only funds cutting-edge cancer research but also provides hope for patients who are dealing with this terrible disease.”
Fatatis won his grant for his research in cancer development. “It is virtually impossible for any PA resident not to be affected by the impact exerted by breast and cervical cancer on family, workplace and human society at large,” said Fatatis.

More than $3 million has been donated to the Refunds for Research campaign, which allows Pennsylvania taxpayers to donate their state tax refunds directly to this important work. More than 80 Refunds for Research grants have been awarded to Pennsylvania scientists looking for the cause of and cure for breast cancer. All Pennsylvania residents can contribute to the PBCC’s Refunds for Breast Cancer Research fund through the PA-40 income tax form by choosing code “A” on line 32.

For More Information see the Drexel Press Release

MEDIA CONTACT
Ed Federico
Media Relations Manager
215.255.7331
Edward.federico@drexelmed.edu



Dr. Carmine Fedele is awarded an AICF Fellowship

Dr. Carmine Fedele

Dr. Carmine Fedele

Carmine Fedele, PhD, a post-doctoral fellow in Dr. Languino’s lab, has been awarded a 2014-2015 Fellowship (2nd year) from the American Italian Cancer Foundation. His project involves determining the effect of integrin expression on the composition and function of exosomes in prostate cancer cells. For more details about the American Italian Cancer Foundation, please see their website




Dr. Nevalainen wins SKCC Innovator of the Year Award

Drs. Pestell and Nevalainen

Drs. Pestell and Nevalainen

On December 16, 2014, Dr. Marja Nevalainen was awarded the 2014 Sidney Kimmel Cancer Center Innovator of the Year award. The award was presented presented by Dr. Richard G. Pestell, Director of the Sidney Kimmel Cancer Center.




Dr. Tu Dan Awarded ASTRO Seed Grant

Dr Tu Dan

Dr Tu Dan

The American Society for Radiation Oncology (ASTRO) has awarded Dr. Tu Dan a 2014 Resident/Fellows in Radiation Oncology Research Seed Grant.  The ASTRO Research Evaluation Committee and Board of Directors were pleased to recognize Dr. Dan’s application based upon its scientific merit. Dr. Dan will be provided with a one-year grant in the amount of $25,000.  Dr. Dan was selected from over 50 applicants and only 2 grants were given.




Amanda Taylor Receives 5 Year NCI Fellowship

Amanda Taylor

Amanda Taylor

Amanda Taylor, a doctoral candidate in the Genetics, Genomics and Cancer Biology Program conducting her thesis research in the laboratory of Dr. Steven McMahon has received a 5 year fellowship from the National Cancer Institute/NIH totaling $221,400. The award was made for a project entitled: “Myc overexpression regulates metabolic reprogramming by mitochondrial polymerase”.




Dr. Curry Receives Grant to Investigate Head and Neck Cancer

Joseph Curry, MD

Joseph Curry, MD

Joseph Curry, MD, Assistant Professor in the Department of Otolaryngology – Head and Neck Surgery, has been selected to receive this year’s American Head and Neck Society/American Academy of Otolaryngology-Head and Neck Surgery Foundation Young Investigators Combined Grant. Under the mentorship of Dr. Ubaldo Martinez-Outschoorn, Assistant Professor of Medical Oncology and Dr. William Keane, Chairman of the Department of Otolaryngology – Head and Neck Surgery, Dr. Curry will investigate metabolic coupling between cancer and stromal cells in head and neck cancer and its role in carcinoma cell proliferation and resistance to apoptosis.

The American Academy of Otolaryngology-Head and Neck Surgery Centralized Otolaryngology Research Efforts (CORE) grants program is a collaboration of several societies, foundations, and industry supporters focused on providing support for research in the field of otolaryngology-head and neck surgery.




Dr. Gabriele Di Sante Awarded American Italian Cancer Foundation Research Fellowship

Dr. Gabriele Di Sante

Dr. Gabriele Di Sante

Gabriele Di Sante, PhD, a post-doctoral fellow in Dr. Pestell’s lab, has been awarded a 2014-2015 Fellowship from the American Italian Cancer Foundation. For more details about the American Italian Cancer Foundation, please see their website.



Dr. Aplin Wins Innovation Award

Dr. Andrew Aplin

Dr. Andrew Aplin

Congratulations to Dr Andrew Aplin, Department of Cancer Biology, has received the 2014 Jefferson Medical College Michael and Melina Pellini Award for Innovation in the Biomedical Sciences. The award is given “For the elucidation/description of a specific discovery, technique, or instrument/device that has led to new concepts or approaches to experimentation or patient care.”




Dr. Richard Pestell Receives Advance Global Australian Award in Biotechnology Category

Former Australian Prime Minister John Howard and Dr, Richard Pestell

Former Australian Prime Minister John Howard and Dr, Richard Pestell

Dr. Pestell received the award for his work at the Kimmel Cancer Center at Jefferson as well as Prostagene, LLC, which is a biotechnology company he founded. Please see this Financial Review Article for more information bout this year’s Advance Global Australian Awards. Also please see this video clip of Dr. Pestell receiving the Advance Global Australian Award in Biotechnology at the Sydney Opera House.



Dr. Gomella elected to the Clinical Society of Genitourinary Surgeons

Dr. Leonard Gomella

Dr. Leonard Gomella

Leonard G. Gomella, MD, The Bernard W. Godwin Professor of Prostate Cancer, Chairman, Department of Urology, Associate Director, Jefferson Kimmel Cancer Center, Clinical Director Jefferson Kimmel Cancer Center Network, Editor-in-Chief, Canadian Journal of Urology has been elected to the Clinical Society of Genitourinary Surgeons. This is considered one of the most prestigious societies in the field with active membership limited to 25 of the top academic urologists in the US.



ACS-IRG Pilot Projects Awarded for 2013

Left to Right: Dr. Jordan Winter, Dr. Lara Weinstein, Dr. Aejaz Sayeed, Dr. Richard Pestell, Dr. Tali Gidalevitz, Larry Slagle, Ruth Ann Dailey, Dr. Marja Nevalainen

The Jefferson Kimmel Cancer Center hosted the Annual ACS-IRG Luncheon on September 17th to announce the 2013 Pilot Project award recipients from Thomas Jefferson University. Awardees include Sheikh Aejaz Sayeed, PhD from the Department of Cancer Biology; Jordan Winter, MD, from the Department of Surgery; Yaron Moshel, MD, PhD from the Department of Neurological Surgery; Tiffany Avery, MD, MPH from the Department of Medical Oncology; Lara Carson Weinstein, MD, MPH from the Department of Family & Community Medicine and from Drexel University,  Tali Gidalevitz, PhD from the Department of Biology. Each Awardee briefly explained their research projects to Ruth Ann Dailey, Vice President, Corporate and Distinguished Partners and Larry Slagle, Distinguished Giving Director, of the East Central Division of the American Cancer Society. Ms. Dailey and Mr. Slagle explained the ACS mission and offered ways in which the Pilot Project recipients would be able to assist them in that mission.



Kimmel Cancer Center “All Hands Meeting”

The Kimmel Cancer Center held it’s quarterly “All Hands” meeting on September 11, 2013. Dr. Richard Pestell, Director of the Kimmel Cancer Center, delivered his quarterly “State of the Cancer Center” address. Awards were presented in several categories. Two “Special Recognition” awards where presented to  Andrew Quong, PhD and Jeanine Voll (not pictured). The “Discovery of the Year” Awards was presented to Alexander Mazo, PhD. The Nursing Award was presented to Tamara McGovern, RN. The Basic Science Award was awarded to Dr. Andrew Aplin (not pictured). A Special Team Nursing Award was presented to  the ONCare Nursing team. A Special Administration Award was present to the ONCare Administrative Team.

Dr. Alexander Mazo Receives "Discovery of the Year" Award from Dr. Richard Pestell

Dr. Alexander Mazo Receives "Discovery of the Year" Award from Dr. Richard Pestell

Dr. Andrew Quong Receives "Special Recognition" Award from Dr. Richard Pestell

Dr. Andrew Quong Receives "Special Recognition" Award from Dr. Richard Pestell



ONCare Administrative Team Receives Special team Admimistration Award From Dr. Neal Flomenberg

ONCare Administrative Team Receives Special team Admimistration Award From Dr. Neal Flomenberg



ONCare Nursing Team Receives Special Team Nursing Award From Dr. Neal Flomenberg

ONCare Nursing Team Receives Special Team Nursing Award From Dr. Neal Flomenberg


Ms. Tamara McGovern Receives Nursing Award from Dr. Neal Flomenberg

Ms. Tamara McGovern Receives Nursing Award from Dr. Neal Flomenberg





KCC Researchers Awarded $480,000 from Breast Cancer Research Foundation

Richard Pestell, MD, PhD and Andrew Quong, PhD

The Breast Cancer Research Foundation recently announced that Dr. Richard Pestell and Dr. Andrew Quong received unanimous approval for studies in breast cancer, the second most prevalent cancer-related cause of death in women in the United States.

Beginning October 1, 2013, Dr. Pestell will receive $240,000 to continue the “Molecular Genetic determinants of Breast Cancer Stem Cells” study and Dr. Quong will receive $240,000 to continue the “Clinical Proteomics for Breast Cancer Diagnostics” study.

Dr. Pestell’s study will focus on basal breast cancer including triple negative breast cancer, defined by the absence of three receptors (estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 [HER2]). Triple negative breast cancer is prominent among African-American women, and currently no targeted therapies for this type of breast cancer exist. Within human breast cancer a subset of cells have characteristics of stem cells (BTIC), which may contribute to recurrence and therapeutic resistance. The mechanism by which the gene DACH1 inhibits BTIC is being determined as a new approach to enhance therapeutic responsiveness. Dr. Pestell’s findings over the last year that DACH1 binds to and enhances function of the p53 tumor suppressor, but fails to bind mutations of p53 identified in human breast cancer, adds further weight to the original hypothesis that DACH1 is a breast tumor suppressor. Dr. Pestell’s studies in 2012-2013 will continue to define the role of endogenous DACH1 as a breast cancer suppressor.

Support from BCRF has also allowed Dr. Quong to complete his studies examining changes in protein levels in breast tumors. From these observed changes, Dr. Quong’s team found changes in the metabolism of tumor cells that are related to the local microenvironment of the tumor. These changes in metabolism can potentially be exploited for both imaging and drug development. In addition, Dr. Quong has continued his work identifying markers that are indicators of toxicity and response to therapy.

In 2012-2013, the goal of Dr. Quong’s research is to determine new strategies for patient treatment that include radiation therapy. By measuring the protein and gene expression in tumors, his will use this information for choosing treatment and also monitoring the patients’ response to treatment both for effectiveness and adverse side effects.



KCC Ranked as One of Best Cancer Hospitals in US

Men’s Health magazine recently ranked the Kimmel Cancer Center at Jefferson among the best in the nation, calling out its success in treating prostate cancer, a leading cancer in men.

The American Cancer Society estimates there will be more than 1.5 million new cancer diagnoses in 2013.

Jefferson scientist, Matthew Schiewer, Ph.D., recently received the Prostate Cancer Benjamin Franklin Young Investigator Award, and will use the funds to help find treatments for advanced-stage prostate cancers.

Jefferson is home to top-of-the-line equipment and high-tech features like electron and photon-beam treatment and complete 3-D treatment planning.  We offer comprehensive diagnostic and treatment options for prostate cancer in addition to state-of-the-art prostate imaging and biopsy service.

When indicated, a prostatectomy can be performed either laparoscopically or via open surgery.  Jefferson physicians were the first in the Delaware Valley to remove the prostate laparoscopically, and have extensive experience with and numerous scientific publications on the use of the da Vinci® Surgical System.

“It is rewarding for our team to be recognized for excellence in cancer care,” says Richard G. Pestell, MD, PhD, MBBS, FRACP, MBA, Kimmel Cancer Center Director.  “We are one of only eight NCI-Designated cancer centers in the United States with a prostate program formally reviewed and endorsed by the National Cancer Institute. This program, led by Leonard Gomella, MD and Karen Knudsen, PhD, is a powerhouse of key advances in prostate cancer.  Our leading edge research and clinical care excellence across a wide spectrum of cancer specialties, including men’s health, enable us to deliver the best outcomes for our patients.”

Kimmel Cancer Center at Jefferson

The Kimmel Cancer Center at Jefferson is a National Cancer Institute (NCI)-designated clinical cancer center for excellence in cancer care and research. U.S.News & World Report also recognizes Jefferson as one of the best hospitals in the nation for Cancer care. Taking into account your varied needs, our nationally renowned cancer experts bring together a team of specialists in a wide range of disciplines to work with you and your primary care or referring physician to devise a personalized treatment plan.

The physicians and scientists of the Kimmel Cancer Center have helped pioneer new approaches to cancer treatment by transforming scientific discoveries into improved patient care. Our physicians are experienced in using the most advanced treatment methods and technologies and are at the forefront of developing new therapies. As a result, you may have the opportunity to take part in one of the more than 120 clinical trials for promising new cancer treatments being conducted at Jefferson at any given time.

by Danielle Servetnick on Tuesday, July 16th, 2013 in Cancer CareIn The News.