Category Breast Cancer


Jefferson Scientists Unlock Secret to Powerful Tumor Suppressor That Can Reverse Cancer Progression

Researchers at the Kimmel Cancer Center at Jefferson have discovered how a powerful tumor suppressor called DACH1 works – a finding that explains why restoring its lost function in cancer cells pushes them to become normal again. In the March 29 online early edition of the Proceedings of the National Academy of Sciences (PNAS), the …


Ladies of Port Richmond Annual Breakfast

The Ladies of Port Richmond held their annual Breakfast fund raiser on Sunday, April 11 2010 at St Adalbert’s School Hall (see the photo gallery). The “Breakfast” also served as a kick-off meeting for the 6th Annual Port Richmond Breast Cancer Walk. The Walk will be held on Sunday, May 16 2010 at 10:00 AM …


Ladies of Port Richmond Support Young KCC Investigators

Thanks to the fundraising efforts of the Ladies of Port Richmond, the Kimmel Cancer Center at Jefferson has awarded six junior investigators with funding for the prevention and improved treatment of breast cancer. The titles of the supported submissions were: John Pascal, Ph.D. Novel Mechanisms For Inhibiting The Cellular Functions Of Parp1 For Cancer Treatment …


Prolactin Blocks Oncogene Associated with Poor Prognosis in Breast Cancer

Researchers from the Kimmel Cancer Center at Jefferson have found a mechanism by which a hormone responsible for milk production blocks an oncogene that makes breast cancer more aggressive. Publishing in the journal Cancer Research, the researchers discovered that prolactin, a pituitary hormone that normally stimulates breast development and milk production, in fact reduces levels …


Rock the Ribbon Black Tie Event, March 27th, 2010

CKC United will host the inaugural "Rock the Ribbon" black tie event. The event will be held on March 27th, 2010 at The Regal Ballroom in Philadelphia, PA. This black tie ball features a delicious four course meal, complimentary beverages, guest speakers, and top notch live music. The formation of CKC United stems from the …


Philadelphia Komen Race for the Cure Recap

The Philadelphia Affiliate of the Susan G. Komen Foundation Race for the CURE held their annual Mother’s Day Race on Sunday, May 10th, 2009. The Kimmel Cancer Center at Jefferson sponsored a booth and Team Jefferson also participated in the race. A few photos from the race below. Gallery


New Universal Breast Cancer Marker Predicts Recurrence

The marker appears to be widely applicable to all breast cancer patients, regardless of other established prognostic indicators Reporting online in the American Journal of Pathology, researchers from the Kimmel Cancer Center at Jefferson have implicated the loss of a stromal protein called caveolin-1 as a major new prognostic factor in patients with breast cancer, …


Ladies of Port Richmond 5th Annual Breast Cancer Walk

View Larger Map A reminder that The Ladies of Port Richmond will be holding their annual Breast Cancer Walk on Sunday, May 17th, 2009. Registration at the walk begins at 8:30 am while the walk starts at 10:00 am. So download the registration form and the pledge form and hit the streets “to increase Breast …


Jefferson’s Kimmel Cancer Center Researchers Receive $6.7 million Grant from Susan G. Komen for the Cure

Researchers from the Kimmel Cancer Center at Jefferson were awarded a Susan G. Komen for the Cure Promise Grant of almost $6.7 million for five years for continued breast cancer research. The project represents a multidisciplinary team of scientists from a consortium that also includes Walter Reed Army Medical Center and DecisionQ Inc. in Washington …


Jefferson Breast Cancer Researcher to Receive PA Income Tax Check-Off Grant

Hallgeir Rui, M.D., Ph.D, a professor of Cancer Biology at Jefferson Medical College of Thomas Jefferson University and Jefferson’s Kimmel Cancer Center, is one of three recipients of the Income Tax Check-Off for Breast & Cervical Cancer Research grants this year. The $50,000 award will be used to conduct research to understand what causes the …


Therapy May Block Expansion of Breast Cancer Cells

Breast cancer stem cells are known to be involved in therapy resistance and the recurrence of cancerous tumors. A new study appearing in Clinical and Translational Science shows the mechanisms governing stem cell expansion in breast cancer (called Notch activity), and finds that therapy targeting a protein called cyclin D1 may block the expansion of …


Jefferson Researchers Show Antibody to Breast Cancer- Secreted Protein Blocks Metastasis

Scientists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have made a key discovery about the mechanism of breast cancer metastasis, the process by which cancer spreads. Focusing on a gene dubbed “Dachshund,” or DACH1, they are beginning to pinpoint new therapeutic targets to halt the spread of cancer. Reporting their findings …

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