Category Cancer Types

19
May

Small RNA Molecules Block Breast Cancer from Spreading via Newly Identified Secreted Factor

The role of genes and proteins in cancer control is well known, but now researchers at Jefferson’s Kimmel Cancer Center have found a cluster of microRNA (miRNA) molecules that act to suppress the invasive spread of breast cancer. MiRNAs are non-coding small RNA molecules found in wide areas of the genome that, either singly or …

19
May

Clue to Switch of Bladder Cancer from Locally Contained to Invasive Found by Jefferson Scientists

Bladder cancer often becomes aggressive and spreads in patients despite treatment, but now researchers at the Kimmel Cancer Center at Jefferson have identified a protein they believe is involved in pushing tumors to become invasive – and deadly. “We have found that IGF-IR is a critical regulator of motility and invasion of bladder cancer cells, …

19
May

Jefferson Scientists Unlock Secret to Powerful Tumor Suppressor That Can Reverse Cancer Progression

Researchers at the Kimmel Cancer Center at Jefferson have discovered how a powerful tumor suppressor called DACH1 works – a finding that explains why restoring its lost function in cancer cells pushes them to become normal again. In the March 29 online early edition of the Proceedings of the National Academy of Sciences (PNAS), the …

14
Apr

Ladies of Port Richmond Annual Breakfast

The Ladies of Port Richmond held their annual Breakfast fund raiser on Sunday, April 11 2010 at St Adalbert’s School Hall (see the photo gallery). The “Breakfast” also served as a kick-off meeting for the 6th Annual Port Richmond Breast Cancer Walk. The Walk will be held on Sunday, May 16 2010 at 10:00 AM …

2
Apr

Dr. Leonard G. Gomella Studies the Effect of Dutasteride on the Risk of Prostate Cancer

Dr. Leonard G. Gomella and colleagues conducted a landmark international randomized, double-blind, placebo-controlled, parallel-group multi-center clinical trial to determine whether dutasteride reduces the risk of incident prostate cancer, as detected on biopsy, among men who are at increased risk for the disease. Over the course of the 4-year study period, dutasteride reduced the risk of …

30
Mar

Karen Knudsen receives Richard E. Weitzman Memorial Award

Karen Knudsen, PhD, Associate Professor, Department of Cancer Biology and Urology at the Kimmel Cancer Center received the Richard E. Weitzman Memorial Award from the Endocrine Society. This annual Laureate Awards annual award recognizes an exceptionally promising young clinical or basic investigator. Knudsen is recognized for scientific achievements in the study of androgen action in …

26
Mar

Second Annual Get Your Rear In Gear Event

The second annual Philadelphia Get Your Rear In Gear will took  place at 7:30 a.m. on Martin Luther King Drive in Philadelphia, Sunday, March 21, 2010, during National Colorectal Cancer Awareness Month.  Both survivors and those lost to colorectal cancer were honored.  There was a 5K Race  and a 2 mile Remembrance Walk. Results are …

23
Feb

Ladies of Port Richmond Support Young KCC Investigators

Thanks to the fundraising efforts of the Ladies of Port Richmond, the Kimmel Cancer Center at Jefferson has awarded six junior investigators with funding for the prevention and improved treatment of breast cancer. The titles of the supported submissions were: John Pascal, Ph.D. Novel Mechanisms For Inhibiting The Cellular Functions Of Parp1 For Cancer Treatment …

22
Feb

Prolactin Blocks Oncogene Associated with Poor Prognosis in Breast Cancer

Researchers from the Kimmel Cancer Center at Jefferson have found a mechanism by which a hormone responsible for milk production blocks an oncogene that makes breast cancer more aggressive. Publishing in the journal Cancer Research, the researchers discovered that prolactin, a pituitary hormone that normally stimulates breast development and milk production, in fact reduces levels …

22
Feb

Inflammation Marker Related to Obesity is Elevated in Patients with Pancreatic Cancer

The levels of an inflammatory chemokine were significantly elevated in patients with pancreatic cancer who were extremely obese, according to research conducted by scientists at the Jefferson Pancreatic, Biliary and Related Cancers Center. They presented their data at the 5th Annual Academic Surgical Congress, held in San Antonio. Studies have shown that obesity is correlated …

2
Feb

Rock the Ribbon Black Tie Event, March 27th, 2010

CKC United will host the inaugural "Rock the Ribbon" black tie event. The event will be held on March 27th, 2010 at The Regal Ballroom in Philadelphia, PA. This black tie ball features a delicious four course meal, complimentary beverages, guest speakers, and top notch live music. The formation of CKC United stems from the …

29
Jun

The Endocrine Society awards KCC scientist

The Endocrine Society is pleased to announce the 2009 Laureate Awards established in 1944 to recognize the highest achievements in endocrinology including: science, leadership, teaching and service. This year’s Laureate Awards were presented at ENDO 09, the 91st Annual Meeting of The Endocrine Society, being held June 10-13, in Washington, DC. Karen Knudsen, PhD, Associate …

29
Jun

Stromal Biomarker Predicts Advanced Prostate Cancer

The same biomarker was previously identified as a prognostic factor for breast cancer The absence of a stromal protein called caveolin-1 appears to be a marker for advanced prostate cancer and metastasis, researchers from the Kimmel Cancer Center at Jefferson and Harvard Medical School reported in Cell Cycle. There was an abundance of stromal caveolin-1 …

27
May

Philadelphia Komen Race for the Cure Recap

The Philadelphia Affiliate of the Susan G. Komen Foundation Race for the CURE held their annual Mother’s Day Race on Sunday, May 10th, 2009. The Kimmel Cancer Center at Jefferson sponsored a booth and Team Jefferson also participated in the race. A few photos from the race below. Gallery

21
May

New Universal Breast Cancer Marker Predicts Recurrence

The marker appears to be widely applicable to all breast cancer patients, regardless of other established prognostic indicators Reporting online in the American Journal of Pathology, researchers from the Kimmel Cancer Center at Jefferson have implicated the loss of a stromal protein called caveolin-1 as a major new prognostic factor in patients with breast cancer, …

13
May

Run 4 Your Life 5K Run/Walk

The Seventh Annual Run 4 Your Life Run/Walk and 1 Mile Fun Walk to benefit Prostate Cancer Research and Awareness will be happening this year on June 21st. Jefferson/KCC already have a team setup but have a long way to go to reach our goal of $1000. The standard registration fee is $25, but if …

13
May

Thymoquinone Inhibits the Development of Pancreatic Cancer

An herb recently found to kill pancreatic cancer cells also appears to inhibit development of pancreatic cancer as a result of its anti-inflammatory properties, according to researchers from the Kimmel Cancer Center at Jefferson. The data were presented at the AACR 100th Annual Meeting 2009 in Denver. (Abstract #494) Thymoquinone, the major constituent of the …

1
May

Melanoma Monday

May is Skin Cancer Detection & Prevention Month, so accordingly this coming Monday is "Melanoma Monday". Although having an unfortunate name, the topic it raises is no laughing matter as skin cancer is the most diagnosed cancer type with over 1 million new diagnosis in the United States each year and rising. So if you …

29
Apr

Ladies of Port Richmond 5th Annual Breast Cancer Walk

View Larger Map A reminder that The Ladies of Port Richmond will be holding their annual Breast Cancer Walk on Sunday, May 17th, 2009. Registration at the walk begins at 8:30 am while the walk starts at 10:00 am. So download the registration form and the pledge form and hit the streets “to increase Breast …

26
Apr

Hypofractionated Stereotactic Radiotherapy Beneficial as Salvage Therapy for Recurrent Low-Grade Glioma

Hypofractionated stereotactic radiotherapy was well-tolerated and improved symptoms in patients with recurrent low-grade glioma, according to researchers from the Kimmel Cancer Center at Jefferson. The data were presented at the AACR 100th Annual Meeting 2009. (Abstract #3617) In a subgroup of patients who also received chemotherapy with their hypofractionated sterotactic radiotherapy (H-SRT) the median survival …

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