23
Sep

Dr. Michael Lisanti’s Cancer Research Featured in New Scientist

New cancer research suggests that we have misunderstood the feeding habits of cancer for decades, wrongly believing that cancer cells produce the bulk of their energy by breaking down glucose in the absence of oxygen, known as the Warburg effect. Dr. Michael Lisanti of the Kimmel Cancer Center at Jefferson proposes that when a cell turns cancerous …

22
Sep

New Half-Match Bone Marrow Transplant Procedure Featured in Philadelphia Inquirer

Neal Flomenberg, M.D., chair of the Department of Medical Oncology at Jefferson and Dolores Grosso, DNP, co-principal investigator of the study, have developed a way to make stem-cell transplants work, even when only half the immune markers are matched. Featured in the “Check Up” section of The Philadelphia Inquirer, this research has major implications. Half-match transplants would triple …

8
Sep

Half-Match Bone Marrow Transplant Procedure Yields Promising Outcomes for Cancer Patients

Half-matched bone marrow or stem cell transplants for blood cancer patients have typically been associated with disappointing clinical outcomes. However, a clinical trial conducted at the Kimmel Cancer Center at Jefferson testing its unique, two-step half-match procedure has produced some promising results: the probability of overall survival was 45 percent in all patients after three years …

31
Aug

Edith Mitchell Talks to WHYY Radio about African American Doctors in Medicine

Jefferson medical oncologist Edith Mitchell, M.D., FACP, works on diversity efforts as associate director of Diversity Services for the Kimmel Cancer Center at Jefferson. In a recent WHYY Radio interview, Dr. Mitchell shares some of her experiences with African American patients and gives her perspective on race and medicine today. She believes that listening to patients …

29
Aug

Robert B. Den, M.D., Joins the Department of Radiation Oncology at Jefferson

Radiation oncologist Robert B. Den, M.D., recently joined Thomas Jefferson University Hospital as an attending physician, and was also named an assistant professor at Jefferson Medical College of Thomas Jefferson University in the Department of Radiation Oncology. Dr. Den is a clinical scientist who specializes in the treatment of prostate cancer, combining his laboratory research …

26
Aug

A Tumor Suppressor May Also Fight Obesity

The hormone receptor guanylyl cyclase C (GCC) has been established as a suppressor of colorectal cancer tumors, but new evidence from Thomas Jefferson University suggests it may also help fight one of the country’s biggest pandemics: obesity. Reporting in the August 25 online issue of the Journal of Clinical Investigation, Scott Waldman, M.D., Ph.D., chairman …

25
Aug

ADVANCE for Nurses Magazine Features KCC’s Senior Adult Oncology Center

The multidisciplinary staff at the Center assesses the many health challenges confronting senior adults and recommends a personalized cancer treatment plan for each patient. Jefferson staff members Pat Dugan, Vicki Squire and Barb Daulerio were interviewed for the article. The nursing magazine, ADVANCE for Nurses, put the spotlight recently on the Senior Adult Oncology Center …

12
Aug

Blocking Receptor in Key Hormone Fires Up Enzyme to Kill Pancreatic Cancer Cells

Pancreatic cancer researchers at Thomas Jefferson University have shown, for the first time, that blocking a receptor of a key hormone in the renin-angiotensin system (RAS) reduces cancer cell growth by activating the enzyme AMPK to inhibit fatty acid synthase, the ingredients to support cell division. With that, a new chemopreventive agent that inhibits the …

2
Aug

Leukemia Drug Reverses Tamoxifen-Resistance in Breast Cancer Cells

Taking a leukemia chemotherapy drug may help breast cancer patients who don’t respond to tamoxifen overcome resistance to the widely-used drug, new research from the Kimmel Cancer Center at Jefferson suggests. Interestingly, researchers found that tamoxifen combined with dasatinib, a protein-tyrosine kinase inhibitor, reverses the chemo-resistance caused by cancer-associated fibroblasts in the surrounding tissue by …

7
Jul

Dr. Greenbaum to co-organize International Conference on Liver Biology

Dr. Linda Greenbaum will co-organize, (along with Dr. Jessica Zucman-Rossi (Professor of Medicine (Oncology), University of Paris Descartes), the 2012 FASEB Summer Research Conference  on “Liver Biology: Fundamental Mechanisms & Translational Applications.  The conference will take place in Snowmass, Colorado July 29-August 3, 2012 and will bring together 150- 200 outstanding basic and translational scientists dedicated …

7
Jul

Dr. Greenbaum selected as Chair of AASLD/ALF Joint Grant Review Committee

Dr. Linda Greenbaum was selected as the  Chair of the  American Association for the Study of Liver Diseases (AASLD)/ American Liver Foundation (ALF) joint grant review committee for the term 2011-14.

5
Jul

Radiation after prostate removal is cost-effective, but less likely to be recommended by urologists

Receiving radiation therapy immediately after a radical prostatectomy is a cost-effective treatment for prostate cancer patients when compared with waiting and acting on elevated prostate-specific antigen (PSA) levels, according to a new study by researchers at Thomas Jefferson University and Hospital. What’s more, a separate, but related study, found that urologists were less likely than …

23
Jun

Director of KCC, Dr. Richard Pestell, in July issue of Runner’s World

Dr. Richard Pestell, director of the Kimmel Cancer Center at Jefferson and former national-class distance runner, was featured in the July issue of Runner’s World. Dr. Pestell spoke with the magazine for the cover story titled “Outrunning Cancer”–which focused on the running community’s ability to raise million of dollars each year to fight cancer. “When …

10
Jun

Edith Mitchell Receives ‘Practitioner of the Year’ Award from Philadelphia County Medical Society

Edith Mitchell, M.D., clinical professor of Medicine and Medical Oncology at Jefferson Medical College of Thomas Jefferson University, was named 2011 “Practitioner of the Year” Award by the Philadelphia County Medical Society (PCMS). For her excellence in clinical care and community service, Dr. Mitchell will be presented the award on Saturday, June 11, during the …

8
Jun

Melanoma Awereness Night At The Philles Organized By Kelly Kroll and the “Bonnie Kroll Melanoma Memorial Fund”

May is Melanoma Awareness Month. Kelly Kroll of Ambler PA has set up the “Bonnie Kroll Melanoma Memorial Fund” in honor of her mother who died in 2001 from uveal melanoma. The fund has raised over $150,000 to support research at the the Thomas Jefferson University Hospital and the Kimmel Cancer Center of Thomas Jefferson …

1
Jun

Dr. Karen Knudsen Receives Ron Ross Award

See the Award Announcement for more information about the Award and its latest recipient. The following was abstracted from the announcement. Dr. Karen Knudsen of the Kimmel Cancer Center received the Ron Ross Award at the 5th Pacific Rim Breast and Prostate Cancer Meeting, held in Kingscliff, Australia, May 3-7, 2011. Dr. Ron Ross was …

1
Jun

KCC Research: Cancer Cells Accelerate Aging & Inflammation in Body to Drive Tumor Growth

Researchers at the Kimmel Cancer Center at Jefferson have shed new light on the longstanding conundrum about what makes a tumor grow—and how to make it stop.  Interestingly, cancer cells accelerate the aging of nearby connective tissue cells to cause inflammation, which ultimately provides “fuel” for the tumor to grow and even metastasize. This revealing …

23
May

Highlights from KCC American Cancer Society Research Symposium

The Kimmel Cancer Center at Jefferson hosted the 3rd Annual American Cancer Society Research Symposium: Celebrating the ACS Institutional Research Grant at KCC on May 6, 2011. Dr. Nevalainen welcomed members of the KCC and TJU community and the American Cancer Society. Richard Pestell, MD, PhD gave the Keynote Address, “Cancer Invasion and Metastasis and …

19
May

Marker Identifies Breast Cancer Patients Likely to Respond to Tamoxifen

ER positive breast cancer patients whose tumors have active protein Stat5 have increased likelihood of responding to anti-estrogen therapy PHILADELPHIA—Cancer researchers at the Kimmel Cancer Center at Jefferson and an international team of collaborators have discovered a biomarker in breast cancer that may help identify which women will respond to anti-estrogen therapy. The research appears …

17
May

Dr. Sato Recieves Generous Gift For Uveal Melanoma Research

Benefactors Mark and Alison Weinzierl pose with Kimmel Cancer Center Director Dr. Richard G. Pestell (R) and Dr. Takami Sato (L), Professor of Medical Oncology and director of the Uveal Melanoma research program at the KCC.  The Weinzierls (from the Dallas, Texas, area) are providing $1 million in support of Dr. Sato’s work.

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