Category Cancer Types

23
Sep

The Ramblewood Country Club Hosted John Runyan’s 2010 “Score For The Cure” Golf Tournament

The Ramblewood  Country Club in Mount Laurel, NJ hosted John Runyan’s 2010 “Score For The Cure” Golf Tournament on September 21st 2010. The proceeds benefited the Kimmel Cancer Center of Jefferson. Dietz & Watson was the Title Sponsor of the event. This  marks the 6th year of the event which has raised nearly $1,000,000 in …

23
Aug

The Ace Club will host the Prostate Cancer Foundation’s 8th Annual Philadelphia Prostate Cancer Fundraiser

The Ace Club will host the Prostate Cancer Foundation’s 8th Annual Philadelphia Prostate Cancer Fundraiser. Clay Hamlin and Neal Rodin invite you to join Michael Milken at the 8th Annual Philadelphia Prostate Cancer Fundraiser.

13
Aug

Free Prostate Cancer Screenings

The Kimmel Cancer Center at Jefferson and Prostate Health International’s Gary Papa Run are offering free prostate screenings as part of a research program. Prostate cancer is the second leading cause of cancer death among men. Screening is important because prostate cancer shows no symptoms in its earliest stages.

24
May

Scientists Find Protein Spurs Spread of Prostate Cancer

Researchers from the Kimmel Cancer Center at Jefferson have found that Stat5, a signaling protein previously found to be key to survival of prostate cancer, is also involved in metastasis. Their study, published in the online edition of Endocrine-Related Cancer, demonstrates in both laboratory and animal models that nuclear Stat5 over-expression leads to a deadly …

19
May

KCC Graduate Student Ethan Abel Receives Award From The Joanna M. Nicolay Melanoma Foundation

Graduate student Ethan Abel has been awarded a Research Scholar Award from the Joanna M. Nicolay Melanoma Foundation. Twenty-four candidates were evaluated for the award. Ethan Abel, a graduate student working with Andrew Aplin, PhD, in the Kimmel Cancer Center, has received a $10,000 Research Scholar Award from the Joanna M. Nicolay Melanoma Foundation. The …

19
May

Small RNA Molecules Block Breast Cancer from Spreading via Newly Identified Secreted Factor

The role of genes and proteins in cancer control is well known, but now researchers at Jefferson’s Kimmel Cancer Center have found a cluster of microRNA (miRNA) molecules that act to suppress the invasive spread of breast cancer. MiRNAs are non-coding small RNA molecules found in wide areas of the genome that, either singly or …

19
May

Clue to Switch of Bladder Cancer from Locally Contained to Invasive Found by Jefferson Scientists

Bladder cancer often becomes aggressive and spreads in patients despite treatment, but now researchers at the Kimmel Cancer Center at Jefferson have identified a protein they believe is involved in pushing tumors to become invasive – and deadly. “We have found that IGF-IR is a critical regulator of motility and invasion of bladder cancer cells, …

19
May

Jefferson Scientists Unlock Secret to Powerful Tumor Suppressor That Can Reverse Cancer Progression

Researchers at the Kimmel Cancer Center at Jefferson have discovered how a powerful tumor suppressor called DACH1 works – a finding that explains why restoring its lost function in cancer cells pushes them to become normal again. In the March 29 online early edition of the Proceedings of the National Academy of Sciences (PNAS), the …

14
Apr

Ladies of Port Richmond Annual Breakfast

The Ladies of Port Richmond held their annual Breakfast fund raiser on Sunday, April 11 2010 at St Adalbert’s School Hall (see the photo gallery). The “Breakfast” also served as a kick-off meeting for the 6th Annual Port Richmond Breast Cancer Walk. The Walk will be held on Sunday, May 16 2010 at 10:00 AM …

2
Apr

Dr. Leonard G. Gomella Studies the Effect of Dutasteride on the Risk of Prostate Cancer

Dr. Leonard G. Gomella and colleagues conducted a landmark international randomized, double-blind, placebo-controlled, parallel-group multi-center clinical trial to determine whether dutasteride reduces the risk of incident prostate cancer, as detected on biopsy, among men who are at increased risk for the disease. Over the course of the 4-year study period, dutasteride reduced the risk of …

30
Mar

Karen Knudsen receives Richard E. Weitzman Memorial Award

Karen Knudsen, PhD, Associate Professor, Department of Cancer Biology and Urology at the Kimmel Cancer Center received the Richard E. Weitzman Memorial Award from the Endocrine Society. This annual Laureate Awards annual award recognizes an exceptionally promising young clinical or basic investigator. Knudsen is recognized for scientific achievements in the study of androgen action in …

26
Mar

Second Annual Get Your Rear In Gear Event

The second annual Philadelphia Get Your Rear In Gear will took  place at 7:30 a.m. on Martin Luther King Drive in Philadelphia, Sunday, March 21, 2010, during National Colorectal Cancer Awareness Month.  Both survivors and those lost to colorectal cancer were honored.  There was a 5K Race  and a 2 mile Remembrance Walk. Results are …

23
Feb

Ladies of Port Richmond Support Young KCC Investigators

Thanks to the fundraising efforts of the Ladies of Port Richmond, the Kimmel Cancer Center at Jefferson has awarded six junior investigators with funding for the prevention and improved treatment of breast cancer. The titles of the supported submissions were: John Pascal, Ph.D. Novel Mechanisms For Inhibiting The Cellular Functions Of Parp1 For Cancer Treatment …

22
Feb

Prolactin Blocks Oncogene Associated with Poor Prognosis in Breast Cancer

Researchers from the Kimmel Cancer Center at Jefferson have found a mechanism by which a hormone responsible for milk production blocks an oncogene that makes breast cancer more aggressive. Publishing in the journal Cancer Research, the researchers discovered that prolactin, a pituitary hormone that normally stimulates breast development and milk production, in fact reduces levels …

22
Feb

Inflammation Marker Related to Obesity is Elevated in Patients with Pancreatic Cancer

The levels of an inflammatory chemokine were significantly elevated in patients with pancreatic cancer who were extremely obese, according to research conducted by scientists at the Jefferson Pancreatic, Biliary and Related Cancers Center. They presented their data at the 5th Annual Academic Surgical Congress, held in San Antonio. Studies have shown that obesity is correlated …

2
Feb

Rock the Ribbon Black Tie Event, March 27th, 2010

CKC United will host the inaugural "Rock the Ribbon" black tie event. The event will be held on March 27th, 2010 at The Regal Ballroom in Philadelphia, PA. This black tie ball features a delicious four course meal, complimentary beverages, guest speakers, and top notch live music. The formation of CKC United stems from the …

29
Jun

The Endocrine Society awards KCC scientist

The Endocrine Society is pleased to announce the 2009 Laureate Awards established in 1944 to recognize the highest achievements in endocrinology including: science, leadership, teaching and service. This year’s Laureate Awards were presented at ENDO 09, the 91st Annual Meeting of The Endocrine Society, being held June 10-13, in Washington, DC. Karen Knudsen, PhD, Associate …

29
Jun

Stromal Biomarker Predicts Advanced Prostate Cancer

The same biomarker was previously identified as a prognostic factor for breast cancer The absence of a stromal protein called caveolin-1 appears to be a marker for advanced prostate cancer and metastasis, researchers from the Kimmel Cancer Center at Jefferson and Harvard Medical School reported in Cell Cycle. There was an abundance of stromal caveolin-1 …

27
May

Philadelphia Komen Race for the Cure Recap

The Philadelphia Affiliate of the Susan G. Komen Foundation Race for the CURE held their annual Mother’s Day Race on Sunday, May 10th, 2009. The Kimmel Cancer Center at Jefferson sponsored a booth and Team Jefferson also participated in the race. A few photos from the race below. Gallery

21
May

New Universal Breast Cancer Marker Predicts Recurrence

The marker appears to be widely applicable to all breast cancer patients, regardless of other established prognostic indicators Reporting online in the American Journal of Pathology, researchers from the Kimmel Cancer Center at Jefferson have implicated the loss of a stromal protein called caveolin-1 as a major new prognostic factor in patients with breast cancer, …

13
May

Run 4 Your Life 5K Run/Walk

The Seventh Annual Run 4 Your Life Run/Walk and 1 Mile Fun Walk to benefit Prostate Cancer Research and Awareness will be happening this year on June 21st. Jefferson/KCC already have a team setup but have a long way to go to reach our goal of $1000. The standard registration fee is $25, but if …

13
May

Thymoquinone Inhibits the Development of Pancreatic Cancer

An herb recently found to kill pancreatic cancer cells also appears to inhibit development of pancreatic cancer as a result of its anti-inflammatory properties, according to researchers from the Kimmel Cancer Center at Jefferson. The data were presented at the AACR 100th Annual Meeting 2009 in Denver. (Abstract #494) Thymoquinone, the major constituent of the …

1
May

Melanoma Monday

May is Skin Cancer Detection & Prevention Month, so accordingly this coming Monday is "Melanoma Monday". Although having an unfortunate name, the topic it raises is no laughing matter as skin cancer is the most diagnosed cancer type with over 1 million new diagnosis in the United States each year and rising. So if you …

29
Apr

Ladies of Port Richmond 5th Annual Breast Cancer Walk

View Larger Map A reminder that The Ladies of Port Richmond will be holding their annual Breast Cancer Walk on Sunday, May 17th, 2009. Registration at the walk begins at 8:30 am while the walk starts at 10:00 am. So download the registration form and the pledge form and hit the streets “to increase Breast …

26
Apr

Hypofractionated Stereotactic Radiotherapy Beneficial as Salvage Therapy for Recurrent Low-Grade Glioma

Hypofractionated stereotactic radiotherapy was well-tolerated and improved symptoms in patients with recurrent low-grade glioma, according to researchers from the Kimmel Cancer Center at Jefferson. The data were presented at the AACR 100th Annual Meeting 2009. (Abstract #3617) In a subgroup of patients who also received chemotherapy with their hypofractionated sterotactic radiotherapy (H-SRT) the median survival …

26
Apr

Vitamin K and Sorafenib Combination Demonstrated Anti-Tumor Effects in Pancreas Cancer and Hepatocellular Carcinoma

A combination of Sorafenib and Vitamin K had an effect in vitro on both human pancreas cancer and hepatocellular carcinoma, according to researchers from the Kimmel Cancer Center at Jefferson. Data from the two studies were presented at the AACR 100th Annual Meeting 2009 in Denver. (Abstract #5470 and #5483) Vitamin K1 or Vitamin K2, …

16
Apr

Therapeutic Effect of Imatinib Improved with Addition of Chloroquine

The therapeutic effects of the blockbuster leukemia drug imatinib may be enhanced when given along with a drug that inhibits a cell process called autophagy, researchers from the Kimmel Cancer Center at Jefferson reported in the Journal of Clinical Investigation. The cell-death effect of imatinib (Gleevec) was potentiated when chloroquine, an autophagy inhibitor, was given …

16
Apr

New Therapeutic Target for Melanoma Identified

A protein called Mcl-1 plays a critical role in melanoma cell resistance to a form of apoptosis called anoikis, according to research published this week in Molecular Cancer Research. The presence of Mcl-1 causes cell resistance to anoikis. This resistance to anoikis enables the melanoma cells to metastasize and survive at sites distant from the …

14
Apr

Jefferson’s Kimmel Cancer Center Researchers Receive $6.7 million Grant from Susan G. Komen for the Cure

Researchers from the Kimmel Cancer Center at Jefferson were awarded a Susan G. Komen for the Cure Promise Grant of almost $6.7 million for five years for continued breast cancer research. The project represents a multidisciplinary team of scientists from a consortium that also includes Walter Reed Army Medical Center and DecisionQ Inc. in Washington …

24
Mar

Jefferson Breast Cancer Researcher to Receive PA Income Tax Check-Off Grant

Hallgeir Rui, M.D., Ph.D, a professor of Cancer Biology at Jefferson Medical College of Thomas Jefferson University and Jefferson’s Kimmel Cancer Center, is one of three recipients of the Income Tax Check-Off for Breast & Cervical Cancer Research grants this year. The $50,000 award will be used to conduct research to understand what causes the …

11
Mar

Proepithelin Encourages Cell Growth and Migration in Prostate Cancer

Researchers from Thomas Jefferson University have identified a protein that appears to play a significant role in the growth and migration of prostate cancer cells, especially androgen-independent prostate cancer cells. The study was published in the American Journal of Pathology. They also found that prostate cancer cells express more of the protein when compared to …

26
Jan

Pre-emptive Treatment Helped Curtail Skin Toxicity with Panitumumab

With a pre-emptive, prophylactic skin regimen, patients who receive panitumumab for treatment of metastatic colorectal cancer may be able to avoid some of the skin-associated toxicities, according to data presented at the 2009 American Society of Clinical Oncology Gastrointestinal Cancers Symposium in San Francisco. Edith Mitchell, M.D., a clinical professor in the Department of Medical …

26
Jan

African-Americans Have Worse Prognosis Compared to Caucasians When Diagnosed With Colorectal Cancer

African-American patients with colorectal were more likely to present with worse pathological features at diagnosis and to have a worse five-year survival rate compared to Caucasian patients, according to a study conducted by researchers at Thomas Jefferson University. The results are being presented at the 2009 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium. …

7
Nov

Therapy May Block Expansion of Breast Cancer Cells

Breast cancer stem cells are known to be involved in therapy resistance and the recurrence of cancerous tumors. A new study appearing in Clinical and Translational Science shows the mechanisms governing stem cell expansion in breast cancer (called Notch activity), and finds that therapy targeting a protein called cyclin D1 may block the expansion of …

7
Jul

Jefferson Researchers Show Antibody to Breast Cancer- Secreted Protein Blocks Metastasis

Scientists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have made a key discovery about the mechanism of breast cancer metastasis, the process by which cancer spreads. Focusing on a gene dubbed “Dachshund,” or DACH1, they are beginning to pinpoint new therapeutic targets to halt the spread of cancer. Reporting their findings …

24
Jun

Different Type of Colon Cancer Vaccine Reduces Disease Spread, Jefferson Scientists Show

Taking advantage of the fact that the intestines have a separate immune system from the rest of the body, scientists at the Kimmel Cancer Center at Jefferson in Philadelphia have found a way to immunize mice against the development of metastatic disease. Reporting online Tuesday, June 24, 2008 in the Journal of the National Cancer …

18
Jun

Blocking Signaling Protein Prevents Prostate Cancer Spread, Jefferson Scientists Find

Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia have shown that by blocking a signaling protein, they can prevent prostate cancer cells from metastatic dissemination. The work opens the door to future studies examining the protein as a target for therapies aimed at keeping prostate cancer at bay. In a series of experiments …

3
Jun

Monitoring Blood Flow Helps Improve Prostate Biopsies, Jefferson Researchers Report

Using a special ultrasound technique to spot areas of blood flow in the prostate gland may substantially reduce the number of unnecessary biopsies, according to a new study by urologists and radiologists at the Jefferson Prostate Diagnostic Center and the Kimmel Cancer Center at Jefferson in Philadelphia. The researchers found that biopsies targeted to areas …

23
May

Traditional Herbal Medicine Kills Pancreatic Cancer Cells, Kimmel Cancer Center at Jefferson Researchers Report

An herb used in traditional medicine by many Middle Eastern countries may help in the fight against pancreatic cancer, one of the most difficult cancers to treat. Researchers at the Kimmel Cancer at Jefferson in Philadelphia have found that thymoquinone, an extract of Nigella sativa seed oil, blocked pancreatic cancer cell growth and killed the …

14
Apr

Jefferson Scientists’ Discovery May Help Explain Smoking-Pancreatic Cancer Link

If lung cancer and heart disease aren’t bad enough, cigarette smokers are also at higher risk for developing, among other things, pancreatic cancer. Now, researchers at the Kimmel Cancer at Jefferson in Philadelphia have preliminary evidence indicating one possible reason why. Data being presented April 13, 2008 during the Annual Meeting of the American Association …

14
Apr

Blood Pressure Drugs Halt Pancreatic Cancer Cell Growth, Jefferson Researchers Find

Researchers at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia are inching closer to understanding how common blood pressure medications might help prevent the spread of pancreatic cancer. They have found in the laboratory that one type of pressure-lowering drug called an angiotensin receptor blocker inhibits pancreatic cancer cell growth and causes cell …

3
Apr

Jefferson, PanCAN Holding Program April 5 to Help Patients, Families, and Public Learn More About Pancreatic Cancer

The message about pancreatic cancer is changing, says renowned surgeon Charles J. Yeo, M.D. New imaging techniques, improved early detection and screening of high-risk groups, and new therapies on the horizon have begun to change the way pancreatic cancer is viewed. “There’s been a shift in the way we treat and think about this disease,” …

29
Feb

Blocking Growth Protein Kills Prostate Cancer Cells, Inhibits Tumor Growth, Jefferson Scientists Find

Researchers at Jefferson’s Kimmel Cancer Center in Philadelphia have shown that they can effectively kill prostate cancer cells in both the laboratory and in experimental animal models by blocking a signaling protein that is key to the cancer’s growth. The work proves that the protein, Stat5, is both vital to prostate cancer cell maintenance and …

27
Feb

New Jefferson Trial to Test Radiation-Emitting Beads Against Advanced Liver Cancer

Liver cancer specialists at Jefferson’s Kimmel Cancer Center in Philadelphia are beginning an 18-month study of a new treatment for liver cancer. The therapy entails injecting tiny beads that emit small amounts of radiation into the liver’s main artery while also blocking the blood supply feeding the cancer’s growth. The technique, called radioembolization, has been …

21
Jan

Jefferson Scientists Find Protein Helps Pancreatic Cancer Cells Hide from Immune System, Allowing Spread

A protein that helps prevent a woman’s body from rejecting a fetus may also play an important role in enabling pancreatic cancer cells to evade detection by the immune system, allowing them to spread in the body. Researchers at Jefferson’s Kimmel Cancer Center in Philadelphia found that the metastatic cancer cells in the lymph nodes …

3
Jan

Jefferson Scientists Find Cell Growth Protein Potential Drug Target for Treatment-Resistant Prostate Cancer

Scientists at Jefferson’s Kimmel Cancer Center in Philadelphia have found that a signaling protein that is key to prostate cancer cell growth is turned on in nearly all recurrent prostate cancers that are resistant to hormone therapy. If the findings hold up, the protein, called Stat5, may be a specific drug target against an extremely …

3
Jan

“C” to Believe: Jefferson Scientists Studying the Effects of High Dose Vitamin C on Non-Hodgkin Lymphoma Patients

Scientists at Thomas Jefferson University Hospital and Jefferson’s Kimmel Cancer Center have received approval for a first-of-its kind study on the effect high dose vitamin C has on non-Hodgkin lymphoma patients. Researchers from the Jefferson-Myrna Brind Center of Integrative Medicine and Kimmel Cancer Center in conjunction with the National Institutes of Health will study whether …

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