17
Feb

Five Easy Ways to Lower Your Cancer Risk

February is National Cancer Prevention Month. Below are 5 easy ways to help reduce your risk of developing cancer, thanks to Amy Leader, PhD, and Charnita Zeigler-Johnson, PhD, both Assistant Professors in the Department of Medical Oncology.  1. Healthy diet It is well known that a poor diet can lead to being overweight or obese, which …

27
Jan

The Sidney Kimmel Cancer Center at Jefferson Welcomes Pierluigi Porcu

The Sidney Kimmel Cancer Center at Jefferson is pleased to announce the appointment of Pierluigi Porcu, MD, as the new Director of the Hematologic Malignancies and Hematopoietic Stem Cell Transplantation Division in the Department of Medical Oncology, effective December 1, 2016. Dr. Porcu comes to Jefferson from The Ohio State University in Columbus, where he …

13
Jan

Maria Werner-Wasik Receives New Jefferson Appointments

The Sidney Kimmel Cancer Center at Jefferson is pleased to announce that Maria Werner-Wasik, MD, FASTRO, has been appointed to the position of Executive Vice Chair for Radiation Oncology Integration and the Walter Curran Professor of Radiation Oncology.  As the Executive Vice Chair, she will focus her activities on harmonizing and integrating all clinical radiation …

7
Dec

Jefferson Breast Cancer Researcher Named Margaret Q. Landenberger Professor

Nicole Simone, MD, has been named the Margaret Q. Landenberger Professor. The professorship, which focuses on breast cancer research, was established in 2006 by the Margaret Q. Landenberger Research Foundation. Dr. Simone will be the second holder of the professorship. “Dr. Simone is a cancer research pioneer who has dedicated her entire career to discovering …

21
Nov

Dr. Sara Meyer Joins Sidney Kimmel Cancer Center

The Sidney Kimmel Cancer Center at Jefferson is pleased to announce the appointment of Sara Meyer, PhD, as a new assistant professor in the department of Cancer Biology effective November 1, 2016. Previously, Dr. Meyer was a postdoctoral fellow at Cincinnati Children’s Hospital Medical Center. Dr. Meyer received her PhD in Cell and Molecular Cancer …

26
Oct

Dr. Grace Lu-Yao Joins Jefferson

Grace Lu-Yao, PhD, MPH, recently joined the Sidney Kimmel Cancer Center at Jefferson as part of the center’s growing population science program. She is now serving as the Associate Director for Population Science at the Sidney Kimmel Cancer Center at Jefferson and the Vice Chair and professor in the department of medical oncology at the …

11
Oct

Dr. Andrew Chapman Named Interim Chief of Cancer Services

To address the needs and complexity of our growing enterprise, Sidney Kimmel Cancer Center at Jefferson (SKCC) has announced that Andrew Chapman, DO, FACP, will serve in an interim role as the new enterprise-wide Chief of Cancer Services, a role that will also include Aria-Jefferson Health and Abington-Jefferson Health. Dr. Chapman brings significant expertise from …

13
Sep

2016 ASTRO Annual Meeting

The American Society for Radiation Oncology (ASTRO) Annual Meeting is the premier radiation oncology scientific event in the world and draws more than 11,000 attendees each year. The 2016 Annual Meeting, taking place Sept. 25-28 at the Boston Convention and Exhibition Center, will feature research from various members of the department of radiation oncology at …

7
Sep

Teen Wraps Cancer Patients in Love

Like many teenagers, Eve Korus, 17, has a lot on her plate. The Westport, Conn. high school senior keeps busy with homework, college planning, and soccer, but she still finds time to give back to the community — especially patients undergoing chemotherapy treatment for cancer. On Aug. 30, patients and employees at the Jefferson Infusion …

23
Dec

Two SKCC PhD Students Invited To Present Research At International Meetings

Congratulations to two PhD students in Dr. Karen Knudsen’s laboratory who have been invited to speak at upcoming Keystone Symposia on Molecular and Cellular Biology!! Jennifer Jones McMann, a student in the Genetics, Genomics and Cancer Biology PhD Program, will present “Novel Action of p53 Gain-of-Function Mutation in Prostate Cancer Progression” at the Keystone Conference …

9
Nov

The Perfect Match Might Be the Imperfect One

When it comes to treating blood cancers like leukemia and lymphomas, new research shows that a half-matched donor bone marrow transplant may be just as good as a full match, in the first apples to apples type comparison of its kind. (PHILADELPHIA) – Bone marrow transplantation is a life-saving therapy for many patients with blood …

30
Oct

Immune Cell Delivers ‘Kiss of Death’ to Cancer

The immune system plays a major role in cancer, from seeking out and destroying cancer cells when they first form, to eventually being overcome and even co-opted to ignore or protect the tumor mass. Clinicians and researchers have been investigating how best to boost and re-activate the immune system’s natural ability to attack cancer.  Now …

14
Apr

DOD Grant Awarded To Drs. Zeigler-Johnson and Amy Leader

Charnita Zeigler-Johnson, PhD, Assistant Professor of Medical Onoclogy and Amy Leader, PhD, Assistant Professor of Medical Oncology have been awarded a DOD Synergistic Award to support a project called, “A neighborhood-based intervention to reduce prostate cancer disparities.” This grant is a 3-year award. Dr. Ziegler Johnson will be serving as s the PI, and Dr. …

14
Apr

Dr. Myers Invited To Share His Research At Preventive Oncology Meeting

Ronald Myers, PhD, Professor of Medical Onocology, was invited to share his work on CRC screening as one of 3 “Best of CEBP” presentations at the recent American Society for Preventive Oncology 39th Annual Meeting in Birmingham, Alabama on March 16, 2015. For more about the ASPO meeting see the agenda  

14
Apr

SKCC Scientists Show That Cancer Cells Can Use Exosome Transfer To Pass On Agressive Traits

Until recently, researchers thought that cell division was the only way for an aggressive cancer cell to pass its traits along. New evidence is showing that cancers can become more dangerous by exporting aggressive traits to neighboring cells via exosomes. These small packages — bubbles — of membrane released into the extracellular environment hold pieces …

9
Mar

Two Drexel University College of Medicine Professors Receive Grants Through Statewide Refunds for Breast Cancer Research Campaign

The Pennsylvania Breast Cancer Coalition recently awarded two Drexel University College of Medicine researchers (and Sidney Kimmel Cancer Center Members) grants from its statewide Refunds for Breast Cancer Research campaign. Alessandro Fatatis, MD, PhD, professor in the Departments of Pharmacology & Physiology and Pathology & Laboratory Medicine, and Mauricio Reginato, PhD, associate professor in the …

17
Feb

New genomic test can direct appropriate use of radiation therapy following prostate surgery

The identification of the right patients for post-operative radiation therapy and the timing of administering that therapy are not easily answered by clinical risk factors alone. The study, published in the Journal of Clinical Oncology, showed that patients with low genomic risk may be optimally managed with observation after radical prostatectomy (prostate surgery), while those …

17
Feb

Dr. William Kevin Kelly appointed leader of the Biology of Prostate Cancer Program

The Sidney Kimmel Cancer Center would like to congratulate Wm. Kevin Kelly, D.O., Professor of Medical Oncology and Director of the Division of Solid Tumor Oncology, on his new appointment as the Leader of the Biology of Prostate Cancer Program.  Dr. Kelly has been a considerable asset to the cancer center and Jefferson as a …

7
Jan

Hold Your Breath to Protect Your Heart

A recent article in the Practical Radiation Oncology was highlighted in Eureka Alerts. The research, performed by members of the Department of Radiation Oncology and the Sidney Kimmel Cancer Center of Thomas Jefferson University, indicated the importance of breathing control during radiation therapy for left breast cancer in protecting the heart from radiation exposure. Harriet …

25
Dec

Dr. Carmine Fedele is awarded an AICF Fellowship

Carmine Fedele, PhD, a post-doctoral fellow in Dr. Languino’s lab, has been awarded a 2014-2015 Fellowship (2nd year) from the American Italian Cancer Foundation. His project involves determining the effect of integrin expression on the composition and function of exosomes in prostate cancer cells. For more details about the American Italian Cancer Foundation, please see …

23
Dec

Dr. Nevalainen wins SKCC Innovator of the Year Award

On December 16, 2014, Dr. Marja Nevalainen was awarded the 2014 Sidney Kimmel Cancer Center Innovator of the Year award. The award was presented presented by Dr. Richard G. Pestell, Director of the Sidney Kimmel Cancer Center.

8
Sep

Dr. Gomella, Associate Director for Clinical Affairs Appointed to NCI Genitourinary Cancers Steering Committee

Dr. Leonard Gomella, Chairman of the Department of Urology and Associate Director for Clinical Affairs for the Sidney Kimmel Cancer at Jefferson has been appointed to serve on the NCI Genitourinary Cancers Steering Committee (GUSC). The GUSC is one of sixteen steering committees formed to leverage current NCI-supported NCTN Groups, Consortia, SPOREs and Cancer Center …

27
Feb

Dr. Gomella elected to the Clinical Society of Genitourinary Surgeons

Leonard G. Gomella, MD, The Bernard W. Godwin Professor of Prostate Cancer, Chairman, Department of Urology, Associate Director, Jefferson Kimmel Cancer Center, Clinical Director Jefferson Kimmel Cancer Center Network, Editor-in-Chief, Canadian Journal of Urology has been elected to the Clinical Society of Genitourinary Surgeons. This is considered one of the most prestigious societies in the …

12
Dec

Jefferon’s Kimmel Cancer Center Holds 5th Annual Men’s Event

Jefferson’s Kimmel Cancer Center hosted its 5th Annual Men’s Event to benefit prostate cancer research and awareness at the Prime Rib Restaurant on November 14. Below are some photos of the night, award ceremony and entertainment provided by Comedy Central’s “100 Greatest Stand-Ups of All Time,” Jim Breuer of Saturday Night Live.

16
Sep

A Link between Hormones and DNA Repair Provide New Clues to Treat Advanced Prostate Cancer

For advanced prostate cancers, new strategies for therapeutic intervention are urgently needed, and require a better understanding of how tumor cells go from slow growth to aggressive behaviors that threaten patient lives. A new study, published by Thomas Jefferson University’s Kimmel Cancer Center researchers in the September 11th online edition of the journal Cancer Discovery, …

9
Sep

KCC Researchers Awarded $480,000 from Breast Cancer Research Foundation

The Breast Cancer Research Foundation recently announced that Dr. Richard Pestell and Dr. Andrew Quong received unanimous approval for studies in breast cancer, the second most prevalent cancer-related cause of death in women in the United States. Beginning October 1, 2013, Dr. Pestell will receive $240,000 to continue the “Molecular Genetic determinants of Breast Cancer …

23
Aug

Researchers Find New Clues to Treat Rare and Aggressive Inflammatory Breast Cancer

A study led by investigators from Thomas Jefferson University’s Kimmel Cancer Center has discovered molecular clues that may help physicians therapeutically target inflammatory breast cancer (IBC), a highly aggressive form of breast cancer. Their study, reported in the June 21 online issue of Breast Cancer Research and Treatment, identified two molecules (ALK and FAK1) involved in the …

23
Aug

Researchers Discover Molecule That Drives Aggressive Breast Cancer

Recent studies by researchers at Thomas Jefferson University’s Kimmel Cancer Center have shown a gene known to coordinate initial development of the eye (EYA1) is a powerful breast tumor promoter in mice. The gene EYA1 was also shown to be overexpressed in a genetic breast cancer subtype called luminal B. The scientists found that excess …

23
Aug

KCC Ranked as One of Best Cancer Hospitals in US

Men’s Health magazine recently ranked the Kimmel Cancer Center at Jefferson among the best in the nation, calling out its success in treating prostate cancer, a leading cancer in men. The American Cancer Society estimates there will be more than 1.5 million new cancer diagnoses in 2013. Jefferson scientist, Matthew Schiewer, Ph.D., recently received the Prostate Cancer Benjamin …

15
Jul

Ladies of Port Richmond Featured in Inquirer

Mary Louise Leuters is a two-time breast cancer survivor and president of the Ladies of Port Richmond, a local group of breast cancer survivors who have raised over $400,000 for breast cancer research in the last nine years.Nearly 300,000 American women will be diagnosed with breast cancer this year, and 40,000 will die from it, …

3
Jul

Keatley Foundation Donation

The Keatley Foundation made a generous $10,000 donation to the Kimmel Cancer Center.   Events like their second annual Beef and Beer contributed to this generous donation. The Keatley Foundation was created by Bob Lyons during his treatment at Jefferson Hospital. The foundation name comes from the street name where Bob lives. According to Bob, That …

18
Jun

KCC Investigator wins Prostate Cancer Foundation Benjamin Franklin Young Investigator Award

Matthew Schiewer, PhD, a postdoctoral fellow in Dr. Karen Knudsen’s lab in the Department of Cancer Biology, is the recent recipient of a Prostate Cancer Foundation Young Investigator Award. Dr. Schiewer’s investigations will focus on the role of PARP-1 in DNA damage repair and the inhibition of PARP with specific medications as a potential therapy …

8
May

Jefferson Post-Doc Receives National Cancer Center Fellowship

Edward Hartsough, Ph.D. received a post-doctoral fellowship from the National Cancer Center Organization ( http://www.nationalcancercenter.org/ ).  The fellowship grant is entitled “Next-Generation RAF Inhibitors in V600E BRAF Melanoma.”  Dr. Hartsough works in Dr. Andrew Aplin’s lab at the Kimmel Cancer Center. The National Cancer Center was founded by Dr. J. Ernest Ayre in 1953 as …

12
Feb

Massimo Cristofanilli, M.D., Appointed Director of the Jefferson Breast Care Center

Massimo Cristofanilli, M.D., FACP, an internationally renowned breast cancer researcher and clinician, has been appointed Director of the Jefferson Breast Care Center at the Kimmel Cancer Center (KCC) and Thomas Jefferson University and Hospitals. With more than 25 years of clinical, basic science and educational experience, Dr. Cristofanilli will also serve as Deputy Director of …

12
Feb

Jefferson Opens Calorie Restriction Trial for Early Stage Breast Cancer Patients on Radiation Therapy

Jefferson’s Kimmel Cancer Center will begin a first-of-its-kind clinical trial that uses calorie restriction to help treat early stage breast cancer patients undergoing radiation therapy. Evidence suggests that reducing patients’ calorie intake could help shrink tumors and improve survival because it enhances the effectiveness of radiation therapy, the team explains in a recent review published …

12
Feb

Jefferson Radiation Oncology Resident Looks to Improve Prostate Cancer Outcomes in Ghana

A new study published in January in the journal BMC Cancer, led by Kosj Yamoah, M.D., Ph.D., a resident in the Department of Radiation Oncology at Thomas Jefferson University and Hospital, takes aim at the issue by investigating prostate cancer diagnoses and treatment delivery in black men living in the West African region, in order …

12
Feb

Phone and Mailed Interventions Significantly Increase Colorectal Cancer Screening Rates

A mailing or phone call to help patients get screened for colorectal cancer significantly increases their chances of actually getting tested, according to a study published in the January issue of Cancer Epidemiology, Biomarkers and Prevention by researchers at the Kimmel Cancer Center at Jefferson. The research team, led by Ronald E. Myers, Ph.D., Professor …

12
Feb

Radiation Oncology Services Expanding at Riddle Hospital

Jefferson Radiation Oncology at Riddle Memorial Hospital is pleased to announce that the expansion of Radiation Oncology services has begun. In the next few months, the Department will begin installing a new True –Beam linear accelerator, Brachytherapy High Dose Rate machine and a CT scanner. Construction is expected to be completed by December 2013. The acquisition of this …

9
Jan

Bench to Bedside: How to Fast Track Targeted Cancer Drugs with Radiation into the Clinic

Researchers from the translational research program of the National Cancer Institute and the Radiation Therapy Oncology Therapy Group have developed new guidelines to help fast track the clinical development of targeted cancer drugs in combination with radiation therapy. The suggested strategic guidelines, published in the Journal of the National Cancer Institute in a recent commentary …

8
Jan

More Designated Time Equals More Published Research for Radiation Oncology Residents

What helps radiation oncologist residents publish more academic research? Giving them more time to do it, physicians in the Department of Radiation Oncology at Thomas Jefferson University Hospital conclude in a study published recently in the Journal of American College of Radiology. Based on results from a web-based survey completed by 97 radiation oncologists and …

21
Dec

Game changing diagnostic & prognostic prostate cancer genetic tests revealed by KCC researchers

Researchers at the Kimmel Cancer Center at Jefferson (KCC) have developed potentially game-changing diagnostic and prognostic genetic tests shown to better predict prostate cancer survival outcomes and distinguish clinically-relevant cancers. The team, led by Richard G. Pestell, M.D., Ph.D., Director of the KCC and the Chair of the Department of Cancer Biology at Thomas Jefferson …

21
Dec

KCC researchers discover new pathways that drive metastatic prostate cancer

Elevated levels of Cyclin D1b could function as a novel biomarker of lethal metastatic disease in prostate cancer patients, according to a pre-clinical study published ahead of print on December 21 in the Journal of Clinical Investigation by researchers at the Kimmel Cancer Center at Jefferson. The group, headed by Karen E. Knudsen, Ph.D., Professor …

23
Oct

Dr. Renato Iozzo appointed as Editor-In-Chief of Matrix Biology

Renato Iozzo, M.D., Ph.D.,  a Professor of Pathology, Anatomy and Cell Biology at Thomas Jefferson University, has recently been appointed as Editor-in-Chief of the journal Matrix Biology beginning January 2013. This flagship journal is published by Elsevier and is affiliated with both the International Society for Matrix Biology and the American Society for Matrix Biology. …

22
Oct

NCI Awards ‘Provocative Questions’ Grant to Thomas Jefferson University Researcher Scott Waldman

Scott Waldman, M.D., Ph.D., chairman of the Department of Pharmacology and Experimental Therapeutics at Thomas Jefferson University, has been awarded one of the prestigious “Provocative Questions”  grants from the National Cancer Institute (NCI) , as part of the Institute’s ambitious program to tackle the “important but not obvious” questions in cancer to ensure no stone …

16
Oct

Stat5 Predicts Outcomes for Prostate Cancer Patients after Radical Prostatectomy

Men who had high levels of the activated Stat5 protein in their prostate cancer after a radical prostatectomy were more likely to have a recurrence or die from the disease compared to men who had little to no presence of the growth protein, according to a recent study published in Human Pathology by Jefferson’s Kimmel …

9
Oct

Doubling up on Advanced Prostate Cancer with PARP Inhibitors

A newly discovered function of PARP-1 could be the key to more effective therapeutics to treat advanced prostate cancer patients, a recent preclinical study published in Cancer Discovery by Jefferson’s Kimmel Cancer Center researchers suggests. The team, led by Karen E. Knudsen, Ph.D., Professor in the Departments of Cancer Biology, Urology, & Radiation Oncology at …

20
Sep

Tissue around tumor holds key to fighting triple negative breast cancer

A natural substance found in the surrounding tissue of a tumor may be a promising weapon to stop triple negative breast cancer from metastasizing. A preclinical study published in PLOS ONE September 19 by Thomas Jefferson University researchers found that decorin, a well-studied protein known to help halt tumor growth, induces a series of tumor …

14
Sep

Jefferson and the Eagles Team Up for Prostate Health and Cancer Awareness

September is Prostate Cancer Awareness month, and Thomas Jefferson University Hospitals has again teamed up with the Philadelphia Eagles to educate fans and others about prostate health and to raise cancer awareness. To help kick off the campaign, Jefferson will serve as the presenting partner at the Sunday, September 16 game versus the Baltimore Ravens, with …

13
Sep

KCC Becomes Provisional ECOG Member

In August, The Eastern Cooperative Oncology Group (ECOG) voted to approve Jefferson’s Kimmel Cancer Center and Thomas Jefferson University Hospital as a Provisional Member. ECOG is one of the largest clinical cancer research organizations in the United States, and conducts clinical trials in all types of adult cancers. It constitutes a large network of private …

7
Sep

Dr. Karen Knudsen Led Group Receives Million Dollar Prostate Cancer Foundation Award

A group of investigators led by Dr. Karen Knudsen was awarded a 2-year challenge grant of one million dollars by the Prostate Cancer Foundation.  The details of this award (from the PCF web site) are: 2012 Movember-PCF Challenge Award Lead Investigator: Karen Knudsen, PhD Thomas Jefferson University Title Interrogation of Aberrant DNA Repair in Sporadic …

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