Category Research

30
Nov

Dr. Den Featured in ASCOPost: Genomic Test Identifies Patients With Prostate Cancer in Need of Intensified Salvage Therapy

Prostate cancer has been slow to catch up with breast cancer in terms of using biomarkers, but a new study represents progress in this regard. A genomic classifier called Decipher® provides important information that can be used to make treatment decisions for men with prostate cancer and a rising prostate-specific antigen (PSA) after radical prostatectomy. …

9
Nov

The Perfect Match Might Be the Imperfect One

When it comes to treating blood cancers like leukemia and lymphomas, new research shows that a half-matched donor bone marrow transplant may be just as good as a full match, in the first apples to apples type comparison of its kind. (PHILADELPHIA) – Bone marrow transplantation is a life-saving therapy for many patients with blood …

29
Oct

Dr. Robert Den featured in ASCO Post

For men with prostate cancer who have had a prostatectomy and salvage radiation therapy, analyzing their tumor genome provides clues as to whether their cancer will metastasize, thereby enabling clinicians to better personalize treatment options, according to research presented by Robert Den, MD.  ASTRO 2015: Genomic Classifier Appears to Predict Metastasis in Patients With Prostate …

26
Jun

Dr. Andrew Aplin Receives New NIH/NCI R01 Grant Award

Congratulations to Dr. Andrew Aplin for receiving a federally award (National Institute of Health/National Cancer Institute) R01 grant for his project: Mutant BRAF-regulated transcription factors in melanoma progression.

14
Apr

Dr. Myers Invited To Share His Research At Preventive Oncology Meeting

Ronald Myers, PhD, Professor of Medical Onocology, was invited to share his work on CRC screening as one of 3 “Best of CEBP” presentations at the recent American Society for Preventive Oncology 39th Annual Meeting in Birmingham, Alabama on March 16, 2015. For more about the ASPO meeting see the agenda  

14
Apr

SKCC Scientists Show That Cancer Cells Can Use Exosome Transfer To Pass On Agressive Traits

Until recently, researchers thought that cell division was the only way for an aggressive cancer cell to pass its traits along. New evidence is showing that cancers can become more dangerous by exporting aggressive traits to neighboring cells via exosomes. These small packages — bubbles — of membrane released into the extracellular environment hold pieces …

17
Feb

New genomic test can direct appropriate use of radiation therapy following prostate surgery

The identification of the right patients for post-operative radiation therapy and the timing of administering that therapy are not easily answered by clinical risk factors alone. The study, published in the Journal of Clinical Oncology, showed that patients with low genomic risk may be optimally managed with observation after radical prostatectomy (prostate surgery), while those …

17
Feb

Dr. William Kevin Kelly appointed leader of the Biology of Prostate Cancer Program

The Sidney Kimmel Cancer Center would like to congratulate Wm. Kevin Kelly, D.O., Professor of Medical Oncology and Director of the Division of Solid Tumor Oncology, on his new appointment as the Leader of the Biology of Prostate Cancer Program.  Dr. Kelly has been a considerable asset to the cancer center and Jefferson as a …

10
Feb

Dr. Andrew Aplin to Lead Basic Science of the Sidney KImmel Cancer Center

Congratulations to Andrew Aplin, PhD, for his appointment to lead Basic Science for the SKCC! Dr. Aplin has already distinguished himself as the leader of the Cancer Cell Biology and Signaling Program, and he will bring his energy and scientific expertise to all aspects of basic research here at the Sidney Kimmel Cancer Center. Please …

23
Dec

Dr. Nevalainen wins SKCC Innovator of the Year Award

On December 16, 2014, Dr. Marja Nevalainen was awarded the 2014 Sidney Kimmel Cancer Center Innovator of the Year award. The award was presented presented by Dr. Richard G. Pestell, Director of the Sidney Kimmel Cancer Center.

22
Oct

2014 SKCC Consortium: Symposium and Poster Session

On October 1st, 2014 the Sidney Kimmel Cancer Center Consortium held a Symposium and Poster Session. Senior Leadership presented overviews of the work being done across the Sidney Kimmel Cancer Center Consortium. Also, progress reports were presented by the recipients of the 2013 SKCC Consortium Pilot Project Awards.  The afternoon portion of the event was …

8
Sep

Dr. Gomella, Associate Director for Clinical Affairs Appointed to NCI Genitourinary Cancers Steering Committee

Dr. Leonard Gomella, Chairman of the Department of Urology and Associate Director for Clinical Affairs for the Sidney Kimmel Cancer at Jefferson has been appointed to serve on the NCI Genitourinary Cancers Steering Committee (GUSC). The GUSC is one of sixteen steering committees formed to leverage current NCI-supported NCTN Groups, Consortia, SPOREs and Cancer Center …

27
Feb

Dr. Gomella elected to the Clinical Society of Genitourinary Surgeons

Leonard G. Gomella, MD, The Bernard W. Godwin Professor of Prostate Cancer, Chairman, Department of Urology, Associate Director, Jefferson Kimmel Cancer Center, Clinical Director Jefferson Kimmel Cancer Center Network, Editor-in-Chief, Canadian Journal of Urology has been elected to the Clinical Society of Genitourinary Surgeons. This is considered one of the most prestigious societies in the …

12
Dec

Jefferon’s Kimmel Cancer Center Holds 5th Annual Men’s Event

Jefferson’s Kimmel Cancer Center hosted its 5th Annual Men’s Event to benefit prostate cancer research and awareness at the Prime Rib Restaurant on November 14. Below are some photos of the night, award ceremony and entertainment provided by Comedy Central’s “100 Greatest Stand-Ups of All Time,” Jim Breuer of Saturday Night Live.

20
Sep

ACS-IRG Pilot Projects Awarded for 2013

The Jefferson Kimmel Cancer Center hosted the Annual ACS-IRG Luncheon on September 17th to announce the 2013 Pilot Project award recipients from Thomas Jefferson University. Awardees include Sheikh Aejaz Sayeed, PhD from the Department of Cancer Biology; Jordan Winter, MD, from the Department of Surgery; Yaron Moshel, MD, PhD from the Department of Neurological Surgery; …

16
Sep

A Link between Hormones and DNA Repair Provide New Clues to Treat Advanced Prostate Cancer

For advanced prostate cancers, new strategies for therapeutic intervention are urgently needed, and require a better understanding of how tumor cells go from slow growth to aggressive behaviors that threaten patient lives. A new study, published by Thomas Jefferson University’s Kimmel Cancer Center researchers in the September 11th online edition of the journal Cancer Discovery, …

9
Sep

KCC Researchers Awarded $480,000 from Breast Cancer Research Foundation

The Breast Cancer Research Foundation recently announced that Dr. Richard Pestell and Dr. Andrew Quong received unanimous approval for studies in breast cancer, the second most prevalent cancer-related cause of death in women in the United States. Beginning October 1, 2013, Dr. Pestell will receive $240,000 to continue the “Molecular Genetic determinants of Breast Cancer …

23
Aug

Researchers Find New Clues to Treat Rare and Aggressive Inflammatory Breast Cancer

A study led by investigators from Thomas Jefferson University’s Kimmel Cancer Center has discovered molecular clues that may help physicians therapeutically target inflammatory breast cancer (IBC), a highly aggressive form of breast cancer. Their study, reported in the June 21 online issue of Breast Cancer Research and Treatment, identified two molecules (ALK and FAK1) involved in the …

23
Aug

Protein in Blood Exerts Natural Anti-Cancer Protection

Researchers from Thomas Jefferson University’s Kimmel Cancer Center have discovered that decorin, a naturally occurring protein that circulates in the blood, acts as a potent inhibitor of tumor growth modulating the tumor microenvironment. The study, published June 24 online in the Proceedings of the National Academy of Sciences (http://www.pnas.org/content/early/2013/06/19/1305732110.abstract), suggests it may be possible to …

23
Aug

Researchers Discover Molecule That Drives Aggressive Breast Cancer

Recent studies by researchers at Thomas Jefferson University’s Kimmel Cancer Center have shown a gene known to coordinate initial development of the eye (EYA1) is a powerful breast tumor promoter in mice. The gene EYA1 was also shown to be overexpressed in a genetic breast cancer subtype called luminal B. The scientists found that excess …

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