Dr. Carmine Fedele is awarded an AICF Fellowship

Dr. Carmine Fedele

Dr. Carmine Fedele

Carmine Fedele, PhD, a post-doctoral fellow in Dr. Languino’s lab, has been awarded a 2014-2015 Fellowship (2nd year) from the American Italian Cancer Foundation. His project involves determining the effect of integrin expression on the composition and function of exosomes in prostate cancer cells. For more details about the American Italian Cancer Foundation, please see their website




ACS-IRG Pilot Projects Awarded for 2013

Left to Right: Dr. Jordan Winter, Dr. Lara Weinstein, Dr. Aejaz Sayeed, Dr. Richard Pestell, Dr. Tali Gidalevitz, Larry Slagle, Ruth Ann Dailey, Dr. Marja Nevalainen

The Jefferson Kimmel Cancer Center hosted the Annual ACS-IRG Luncheon on September 17th to announce the 2013 Pilot Project award recipients from Thomas Jefferson University. Awardees include Sheikh Aejaz Sayeed, PhD from the Department of Cancer Biology; Jordan Winter, MD, from the Department of Surgery; Yaron Moshel, MD, PhD from the Department of Neurological Surgery; Tiffany Avery, MD, MPH from the Department of Medical Oncology; Lara Carson Weinstein, MD, MPH from the Department of Family & Community Medicine and from Drexel University,  Tali Gidalevitz, PhD from the Department of Biology. Each Awardee briefly explained their research projects to Ruth Ann Dailey, Vice President, Corporate and Distinguished Partners and Larry Slagle, Distinguished Giving Director, of the East Central Division of the American Cancer Society. Ms. Dailey and Mr. Slagle explained the ACS mission and offered ways in which the Pilot Project recipients would be able to assist them in that mission.



KCC Investigator wins Prostate Cancer Foundation Benjamin Franklin Young Investigator Award

Matthew Schiewer, PhD

Matthew Schiewer, PhD

Matthew Schiewer, PhD, a postdoctoral fellow in Dr. Karen Knudsen’s lab in the Department of Cancer Biology, is the recent recipient of a Prostate Cancer Foundation Young Investigator Award. Dr. Schiewer’s investigations will focus on the role of PARP-1 in DNA damage repair and the inhibition of PARP with specific medications as a potential therapy for advanced, metastatic prostate cancer. PARP-1 may reduce cancer progression by reducing the activity of the androgen receptor, the engine of prostate cancer. This project is highly translational in nature, and a greater understanding of the relationship between PARP inhibition and AR activity may provide new therapeutic opportunities for prostate cancer patients with advanced disease.

Prostate Cancer Foundation Young Investigator awards are designed to promote long-term careers in the field of prostate cancer research by providing three-year grants for transformational research focused on prostate cancer advances and new treatments to improve patient outcomes. Since 2007, PCF has invested more than $25 million in Young Investigator awards.

Project Title: Determining the translation capacity of the PARP-1/AR axis in prostate cancer

For more info about the 2013 Awards please see the Prostate Cancer Foundation announcement.




Jefferson Post-Doc Receives National Cancer Center Fellowship

Dr. Edward Hartsough

Dr. Edward Hartsough

Edward Hartsough, Ph.D. received a post-doctoral fellowship from the National Cancer Center Organization ( http://www.nationalcancercenter.org/ ).  The fellowship grant is entitled “Next-Generation RAF Inhibitors in V600E BRAF Melanoma.”  Dr. Hartsough works in Dr. Andrew Aplin’s lab at the Kimmel Cancer Center.

The National Cancer Center was founded by Dr. J. Ernest Ayre in 1953 as a non-profit organization committed to research and education about cancer. Melanoma is the deadliest form of skin cancer and its incidence is on the rise. BRAF mutations are found in half of melanomas and the funded work will study new mutant BRAF targeting agents in preclinical models.




ACS-IRG Pilot Projects Awarded for 2012

The Kimmel Cancer Center at Jefferson hosted the Annual ACS-IRG Luncheon on November 11. The 2012 Pilot Project recipients are S. Onder Alpdogan, MD; Amy Leader, DrPh, MPH; and Jianqing Lin, MD; all of the Department of Medical Oncology; Scott Keith, PhD; from the department of Pharmacology & Experimental Therapeutics; Nicole Simone, MD; department of Radiation Oncology; and Christopher Snyder, PhD; department of Microbiology & Immunology. They briefly explained their research projects to Lynne Ayres, MBA, Director of Research Communications, and Larry Slagle, Distinguished Giving Director, of the East Central Division of the American Cancer Society. Ms. Ayres and Mr. Slagle explained the ACS mission and offered ways in which the Pilot Project recipients would be able to assist them in that mission.

Left to Right: Nicole Simone, Jianqing Lin, Marja Nevalainen, Larry Slagle, Lynne Ayres, Christopher Snyder, Amy Leader, and Scott Keith.




Dr. Karen Knudsen and Dr. Renato Iozzo receive Distinguished Mentor Awards.

On Monday, June 11, 2012, at the Annual Jefferson Postdoctoral Research Symposium, Dr. Karen Knudsen and Dr. Renato Iozzo were honored with The Distinguished Mentor Award. The Distinguished Mentor Award was established to recognize Jefferson faculty members that excel in the mentoring of postdoctoral fellows. The award also serves to highlight the importance of positive and effective mentoring of postdoctoral fellows. A good mentor not only teaches his/her mentees but serves as an advocate, advisor and positive role model during the period of direct training and most often, in the following years. It is our hope that the Distinguished Mentor will serve as a model for the entire university and help to enhance the culture of mentoring at Jefferson.



Dr. Jeannie Hoffman-Censits leads Walk for Bladder Cancer

On Saturday, May 5, 2012 Jeannie Hoffman-Censits, M.D. led Team Jefferson from the Kimmel Cancer Center‘s Bluemle Life Sciences Building to Independence Hall. Dr. Hoffman-Censits teamed up with “the first national advocacy organization devoted to bladder cancer,” the Bladder Cancer Advocacy Network, to help raise public awareness of bladder cancer and much needed funding.

Team Jefferson will be walking again on May 4, 2013. For more information, please contact Jessica Soens at Jessica.Soens@JeffersonHospital.org or call 215-955-2054.



Dr. Ronald Myers selected to chair Expert Working Group discussion

Ronald E. Myers, Ph.D.

Ronald Myers, Ph.D., Professor of Medical Oncology and Director of the Division of Population Science at Thomas Jefferson University, has been selected to chair an Expert Working Group discussion at the World Endoscopy Organization meeting on May 18, 2012. The discussion entitled “Improving Population Engagement in Screening” is being held ahead of the DDW Conference in San Diego, CA. and will be the Expert Working Group’s first meeting. The focus of this discussion is Engaging Populations in International CRC Screening Programs.

For more information on this event please contact Dr. Myers at Ronald.Myers@Jefferson.edu or 215-503-4085.



Kimmel Cancer Center Founding Directors Portrait Unveiled


Dr. Richard G. Pestell, Martha Mayer Erlebacher, Dr. Carlo M. Croce, Dr. Richard L. Davidson

A portrait of Dr. Carlo Croce, the founding Director of the Jefferson Kimmel Cancer Center, painted by Philadelphia artist Martha Erlebacher, was unveiled on Tuesday, April 10, 2012, at 4:00 PM in the Bluemle Life Sciences Building.

Martha Mayer Erlebacher has been recognized as one of the leading representational figurative and still-life artists in America who has shown her work nationally and internationally. A number of books and periodicals feature her work, much of which “examines the deep metaphorical and social themes of contemporary culture through her painterly and aesthetic images.”

Dr. Croce is world-renowned for his contributions involving the genes and genetic mechanisms implicated in the pathogenesis of human cancer. He is a member of the National Academy of Sciences and Institute of Medicine in the United States and the Accademia Nazionale delle Scienze detta deiXL in Italy. He has earned a plethora of awards in recognition of his hard work and dedication including two Outstanding Investigator awards from the National Cancer Institute and most recently, an Elected Membership to The American Academy of Arts and Sciences.

Dr. Joesph S. Gonnella and Dr. Carlo M. Croce

Dr. Croce is a principal investigator on eleven federal research grants and has more than 950 peer-reviewed, published research papers. A native of Milan, Italy, Dr. Croce earned his medical degree, summa cum laude, in 1969 from the School of Medicine, University of Rome. He began his career in the United States the following year as an associate scientist at the Wistar Institute of Biology and Anatomy in Philadelphia. In 1980, he was named Wistar Professor of Genetics at the University of Pennsylvania and Institute Professor and Associate Director of the Wistar Institute, titles he held until 1988. From 1988-91, he was Director of the Fels Institute for Cancer Research and Molecular Biology at Temple University School of Medicine in Philadelphia.

In 1991 Dr. Croce was named Director of the Kimmel Cancer Institute at Thomas Jefferson University.  While here, Dr. Croce discovered the role of microRNAs in cancer pathogenesis and progression, implicating a new class of genes in cancer causation.  After thirteen years as Director of the Kimmel Cancer Center, Dr. Croce moved to Ohio State University in 2004.  Under his direction at OSU, faculty within the Human Cancer Genetics Program conduct both clinical and basic research.  Basic research projects focus on how genes are activated and inactivated, how cell-growth signals are transmitted and regulated within cells, and how cells interact with the immune system. Clinical research focuses on discovering genes linked to cancer and mutations that predispose people to cancer.



Director of KCC, Dr. Richard Pestell, in July issue of Runner’s World

July 2011 Issue of Runner's World

Dr. Richard Pestell, director of the Kimmel Cancer Center at Jefferson and former national-class distance runner, was featured in the July issue of Runner’s World.

Dr. Pestell spoke with the magazine for the cover story titled “Outrunning Cancer”–which focused on the running community’s ability to raise million of dollars each year to fight cancer.

“When the story of cancer meets a runner’s story, the combination can be quite powerful,” said Dr. Pestell.

Read the full feature story here: “Outrunning Cancer: Team Effort” by John Brant.

Dr. John Wagner, of the medical oncology department and also a runner, was mentioned in the article, as well.



Edith Mitchell Receives ‘Practitioner of the Year’ Award from Philadelphia County Medical Society

Edith Mitchell, M.D.

Edith Mitchell, M.D., clinical professor of Medicine and Medical Oncology at Jefferson Medical College of Thomas Jefferson University, was named 2011 “Practitioner of the Year” Award by the Philadelphia County Medical Society (PCMS).

For her excellence in clinical care and community service, Dr. Mitchell will be presented the award on Saturday, June 11, during the PCMS President’s Ball at the Ace Conference Center in Lafayette Hill, Pa., celebrating the installation of its 150th president.

“For over 165 years, this society has been advocating for the best in healthcare for all the citizens of Philadelphia,” said Dr. Mitchell, who is also Associate Director for Diversity Programs at the Kimmel Cancer Center at Jefferson. “It’s a great honor to be part of those efforts and recognized for it with this award.”

Dr. Mitchell has spent her medical career helping individuals in medically underserved areas to realize that simple changes in lifestyle can have a dramatic impact on cancer care. Through her work, Dr. Mitchell has demonstrated the importance of community service and outreach especially to those individuals who may not have the means to seek out more conventional medical advice.

She received a bachelor of science in Biochemistry “With Distinction” from Tennessee State University and her medical degree from the Medical College of Virginia in Richmond. Dr. Mitchell entered active duty after completion of her internship and residency in Internal Medicine at Meharry Medical College and a fellowship in Medical Oncology at Georgetown University. She is now a retired Brigadier General from the United States Air Force.

Dr. Mitchell’s research in pancreatic cancer and other gastrointestinal malignancies involves new drug evaluation and chemotherapy, development of new therapeutic regimens, chemoradiation strategies for combined modality therapy, patient selection criteria and supportive care for patients with gastrointestinal cancer.

She travels nationally and internationally teaching and lecturing on the treatment of gastrointestinal malignancies.

As a distinguished researcher, she has received numerous Cancer Research and Principal Investigator Awards, and serves on the National Cancer Institute Review Panel and the Cancer Investigations Review Committee.  She has also authored and co-authored more than 100 articles, book chapters, and abstracts on cancer treatment, prevention, and cancer control.



Dr. Edith Mitchell attends National Summit on Health Disparities, Hon. Nancy Pelosi and Sen. Harry Reid honored

Edith Mitchell, M.D., clinical professor of Medicine and Medical Oncology at Jefferson Medical College of Thomas Jefferson University, attended the 8th Annual National Summit on Health Disparities Meeting & Awards Dinner in Washington, D.C., on April 11 and 12.

Dr. Edith Mitchell and Hon. Nancy Pelosi at the National Summit on Health Disparities. Photo Courtesy of Don Baker/NMQF

The summit, organized by The National Minority Quality Forum and the Congressional Black Caucus Foundation, in collaboration with the CBC Health Braintrust, brings together members of congress, senior healthcare executives, clinicians, payers, and allied members of the healthcare industry to discuss solutions to disease disparities.

Four consummate Americans were honored for their deep commitment and contributions in the area of health care, including Senator Harry Reid and Former Speaker Nancy Pelosi, who both received the Lifetime Achievement Award.

Dr. Mitchell moderated the “Cancer Biomarkers, Clinical Trials, & New Treatment Options” session, which included Roy Herbst, M.D., Ph.D., Chief of Medical Oncology, Yale Cancer Center and Joseph Sparano, M.D., Associate Chairman, Department of Oncology, Montefiore Medical Center.

Francis Collins, M.D., PhD, Director of the National Institutes of Health, also gave a special address.

The National Minority Quality Forum is a non-profit healthcare research and educational organization dedicated to the elimination of health disparities.



Free Prostate Cancer Screenings

11-0199 Prostate Cancer Flyer 2010

The Kimmel Cancer Center at Jefferson and Prostate Health International’s Gary Papa Run are offering free prostate screenings as part of a research program. Prostate cancer is the second leading cause of cancer death among men. Screening is important because prostate cancer shows no symptoms in its earliest stages.

Read more…



Jefferson Commencement Honorees

Drs. Edward C. Bradley, Benjamin S. Carson and Raymond C. Grandon were awarded a Doctor of Science honorary degree from Thomas Jefferson University at the Jefferson Medical College, Jefferson College of Graduate Studies and Jefferson School of Population Health Commencement ceremony on May 24, 2010 at the Kimmel Center for the Performing Arts. Dr. Carson was also the keynote speaker. From more information about the 2010 honorees please see this page

HonoraryDegree

Dr Richard Pestell, Mrs. Nataliia Pestell, Dr. Benjamin Carson, Mrs. Candy Carson, Mr Kenneth Boone and Mrs. Penelope Boone