Archives

23
Feb

Ladies of Port Richmond Support Young KCC Investigators

Thanks to the fundraising efforts of the Ladies of Port Richmond, the Kimmel Cancer Center at Jefferson has awarded six junior investigators with funding for the prevention and improved treatment of breast cancer. The titles of the supported submissions were: John Pascal, Ph.D. Novel Mechanisms For Inhibiting The Cellular Functions Of Parp1 For Cancer Treatment …

22
Feb

Prolactin Blocks Oncogene Associated with Poor Prognosis in Breast Cancer

Researchers from the Kimmel Cancer Center at Jefferson have found a mechanism by which a hormone responsible for milk production blocks an oncogene that makes breast cancer more aggressive. Publishing in the journal Cancer Research, the researchers discovered that prolactin, a pituitary hormone that normally stimulates breast development and milk production, in fact reduces levels …

22
Feb

Inflammation Marker Related to Obesity is Elevated in Patients with Pancreatic Cancer

The levels of an inflammatory chemokine were significantly elevated in patients with pancreatic cancer who were extremely obese, according to research conducted by scientists at the Jefferson Pancreatic, Biliary and Related Cancers Center. They presented their data at the 5th Annual Academic Surgical Congress, held in San Antonio. Studies have shown that obesity is correlated …

8
Feb

2009 Men’s Event Recap

On Tuesday, November, 17th 2009, the Kimmel Cancer Center at Jefferson held the First Annual Men’s Event at the Prime Rib Restaurant in Philadelphia. The Men’s Event was emceed by Comedian Joe Conklin. Special guests included, Mayor Michael Nutter, Don Tollefson, Jon Runyan and Neiman Marcus Models. Guests enjoyed a dinner, silent and live auction, …

2
Feb

Rock the Ribbon Black Tie Event, March 27th, 2010

CKC United will host the inaugural "Rock the Ribbon" black tie event. The event will be held on March 27th, 2010 at The Regal Ballroom in Philadelphia, PA. This black tie ball features a delicious four course meal, complimentary beverages, guest speakers, and top notch live music. The formation of CKC United stems from the …

26
Oct

Edith Mitchell Receives American Cancer Society Cancer Control Award

Edith Mitchell, M.D., clinical professor of Medicine and Medical Oncology at Jefferson Medical College of Thomas Jefferson University, was honored with the Cancer Control Award, an award created by the American Cancer Society. This award recognizes an individual who has made a major and unique contribution to cancer control in a non-research based activity in …

26
Oct

Dr. Renato V. Iozzo Receives Scientific Awards from the Hellenic Society of Biochemistry and Molecular Biology and the Federation of European Biochemical Societies

Renato V. Iozzo, M.D., professor of Pathology and Cell Biology was awarded two plaques and honorary diplomas in recognition of his “Significant Contribution and Scientific Achievements in the fields of Pathobiology and Extracellular Matrices.” The awards were given by the Hellenic Society of Biochemistry and Molecular Biology together with the Hellenic Research Club for Connective …

3
Sep

Edith Mitchell receives National Medical Association Council on Concerns of Women Physicians Pfizer Research Award

Edith Mitchell, M.D., clinical professor of Medicine and Medical Oncology at Jefferson Medical College of Thomas Jefferson University, was honored with the 2009 National Medical Association Council on Concerns of Women Physicians Pfizer Research Award. The award is given to a woman who has made outstanding contributions to clinical or academic medicine. It was presented …

23
Jul

Celebration of Life 2009 Recap

On July 3rd, 2009, the Kimmel Cancer Center at Jefferson celebrated their 10th year Anniversary of their Annual Celebration of Life as well as the 10th year Anniversary of their Buddy Program which matches newly diagnosed cancer patients with a trained cancer survivor (Buddy). The Kimmel Cancer Center at Jefferson is proud to join communities …

6
Jul

Kimmel Cancer Center Inaugural Ball Recap

On Thursday, June 11, 2009, the Kimmel Cancer Center at Jefferson held an Inaugural Ball in Memorial Hall at the Please Touch Museum in Fairmount Park. The Ball was hosted by Caroline & Sidney Kimmel and the lead Sponsor was Ed Snider Foundation and the Comcast-Spectacor Foundation. Honoring Senator Arlen Specter and The American Cancer …

29
Jun

The Endocrine Society awards KCC scientist

The Endocrine Society is pleased to announce the 2009 Laureate Awards established in 1944 to recognize the highest achievements in endocrinology including: science, leadership, teaching and service. This year’s Laureate Awards were presented at ENDO 09, the 91st Annual Meeting of The Endocrine Society, being held June 10-13, in Washington, DC. Karen Knudsen, PhD, Associate …

29
Jun

Stromal Biomarker Predicts Advanced Prostate Cancer

The same biomarker was previously identified as a prognostic factor for breast cancer The absence of a stromal protein called caveolin-1 appears to be a marker for advanced prostate cancer and metastasis, researchers from the Kimmel Cancer Center at Jefferson and Harvard Medical School reported in Cell Cycle. There was an abundance of stromal caveolin-1 …

26
Jun

ACS-IRG Luncheon

The Kimmel Cancer Center at Jefferson hosted the 2nd Annual ACS-IRG Luncheon on June 25, 2009. Representatives of the Southeast Region, Pennsylvania Division of the American Cancer Society had an opportunity to meet this year’s recipients of the Pilot Project Awards from the Kimmel Cancer Center’s American Cancer Society Institutional Research Grant, Richard G. Pestell …

27
May

Philadelphia Komen Race for the Cure Recap

The Philadelphia Affiliate of the Susan G. Komen Foundation Race for the CURE held their annual Mother’s Day Race on Sunday, May 10th, 2009. The Kimmel Cancer Center at Jefferson sponsored a booth and Team Jefferson also participated in the race. A few photos from the race below. Gallery

21
May

New Universal Breast Cancer Marker Predicts Recurrence

The marker appears to be widely applicable to all breast cancer patients, regardless of other established prognostic indicators Reporting online in the American Journal of Pathology, researchers from the Kimmel Cancer Center at Jefferson have implicated the loss of a stromal protein called caveolin-1 as a major new prognostic factor in patients with breast cancer, …

13
May

Run 4 Your Life 5K Run/Walk

The Seventh Annual Run 4 Your Life Run/Walk and 1 Mile Fun Walk to benefit Prostate Cancer Research and Awareness will be happening this year on June 21st. Jefferson/KCC already have a team setup but have a long way to go to reach our goal of $1000. The standard registration fee is $25, but if …

13
May

Thymoquinone Inhibits the Development of Pancreatic Cancer

An herb recently found to kill pancreatic cancer cells also appears to inhibit development of pancreatic cancer as a result of its anti-inflammatory properties, according to researchers from the Kimmel Cancer Center at Jefferson. The data were presented at the AACR 100th Annual Meeting 2009 in Denver. (Abstract #494) Thymoquinone, the major constituent of the …

1
May

Melanoma Monday

May is Skin Cancer Detection & Prevention Month, so accordingly this coming Monday is "Melanoma Monday". Although having an unfortunate name, the topic it raises is no laughing matter as skin cancer is the most diagnosed cancer type with over 1 million new diagnosis in the United States each year and rising. So if you …

29
Apr

Ladies of Port Richmond 5th Annual Breast Cancer Walk

View Larger Map A reminder that The Ladies of Port Richmond will be holding their annual Breast Cancer Walk on Sunday, May 17th, 2009. Registration at the walk begins at 8:30 am while the walk starts at 10:00 am. So download the registration form and the pledge form and hit the streets “to increase Breast …

28
Apr

Alex’s Lemonade Stand™ Foundation for Childhood Cancer Upcoming Events in Philadelphia

Alex’s Lemonade Stand™ Foundation for Childhood Cancer has some upcoming events in the Philadelphia area. The 6th Annual Lemonade Days June 12-14th, The 4th Annual Great Chef’s Event (featuring a number of notable Philly chefs) Wednesday, June 17th, & The Childhood Cancer Symposium on Saturday, June 27th. Also, Kenny Herriot will be pedaling across the …

26
Apr

Hypofractionated Stereotactic Radiotherapy Beneficial as Salvage Therapy for Recurrent Low-Grade Glioma

Hypofractionated stereotactic radiotherapy was well-tolerated and improved symptoms in patients with recurrent low-grade glioma, according to researchers from the Kimmel Cancer Center at Jefferson. The data were presented at the AACR 100th Annual Meeting 2009. (Abstract #3617) In a subgroup of patients who also received chemotherapy with their hypofractionated sterotactic radiotherapy (H-SRT) the median survival …

26
Apr

Vitamin K and Sorafenib Combination Demonstrated Anti-Tumor Effects in Pancreas Cancer and Hepatocellular Carcinoma

A combination of Sorafenib and Vitamin K had an effect in vitro on both human pancreas cancer and hepatocellular carcinoma, according to researchers from the Kimmel Cancer Center at Jefferson. Data from the two studies were presented at the AACR 100th Annual Meeting 2009 in Denver. (Abstract #5470 and #5483) Vitamin K1 or Vitamin K2, …

22
Apr

Jefferson Awarded Highest Honor for Nursing Excellence

Thomas Jefferson University Hospital, Center City Campus, has been granted MAGNET® recognition for nursing excellence from the American Nurses Credentialing Center’s (ANCC) MAGNET Recognition Program®. ANCC is a subsidiary of the American Nurses Association. Less than five percent of the hospitals in the nation have achieved the sought-after MAGNET recognition which honors superior patient care, …

16
Apr

Therapeutic Effect of Imatinib Improved with Addition of Chloroquine

The therapeutic effects of the blockbuster leukemia drug imatinib may be enhanced when given along with a drug that inhibits a cell process called autophagy, researchers from the Kimmel Cancer Center at Jefferson reported in the Journal of Clinical Investigation. The cell-death effect of imatinib (Gleevec) was potentiated when chloroquine, an autophagy inhibitor, was given …

16
Apr

New Therapeutic Target for Melanoma Identified

A protein called Mcl-1 plays a critical role in melanoma cell resistance to a form of apoptosis called anoikis, according to research published this week in Molecular Cancer Research. The presence of Mcl-1 causes cell resistance to anoikis. This resistance to anoikis enables the melanoma cells to metastasize and survive at sites distant from the …

14
Apr

Jefferson’s Kimmel Cancer Center Researchers Receive $6.7 million Grant from Susan G. Komen for the Cure

Researchers from the Kimmel Cancer Center at Jefferson were awarded a Susan G. Komen for the Cure Promise Grant of almost $6.7 million for five years for continued breast cancer research. The project represents a multidisciplinary team of scientists from a consortium that also includes Walter Reed Army Medical Center and DecisionQ Inc. in Washington …

9
Apr

Cancer Programs Celebrate National Cancer Registrars Week,
April 13-17

Theme of “Cancer Registrars….Rock Solid” Emphasizes the Foundation Cancer Registrars Provide for Cancer Research, Awareness, Prevention and Quality Improvement Cancer registrars around the world will join their colleagues and local community leaders to observe the annual National Cancer Registrars Week, April 13–17, 2009. The 2009 theme “Cancer Registrars…Rock Solid” reflects the dependable professionalism cancer registrars …

26
Mar

Jefferson Kimmel Cancer Center Administrator Appointed President-elect of Association of Cancer Executives

Joy Soleiman, MPA, the Clinical Administrator for the Kimmel Cancer Center at Jefferson, has been appointed president-elect of the Association of Cancer Executives. The one-year appointment began in February at the association’s annual meeting. Ms. Soleiman will become president at the association’s annual meeting in 2010, to be held in San Diego. That is also …

24
Mar

Jefferson Breast Cancer Researcher to Receive PA Income Tax Check-Off Grant

Hallgeir Rui, M.D., Ph.D, a professor of Cancer Biology at Jefferson Medical College of Thomas Jefferson University and Jefferson’s Kimmel Cancer Center, is one of three recipients of the Income Tax Check-Off for Breast & Cervical Cancer Research grants this year. The $50,000 award will be used to conduct research to understand what causes the …

11
Mar

Proepithelin Encourages Cell Growth and Migration in Prostate Cancer

Researchers from Thomas Jefferson University have identified a protein that appears to play a significant role in the growth and migration of prostate cancer cells, especially androgen-independent prostate cancer cells. The study was published in the American Journal of Pathology. They also found that prostate cancer cells express more of the protein when compared to …

26
Jan

Pre-emptive Treatment Helped Curtail Skin Toxicity with Panitumumab

With a pre-emptive, prophylactic skin regimen, patients who receive panitumumab for treatment of metastatic colorectal cancer may be able to avoid some of the skin-associated toxicities, according to data presented at the 2009 American Society of Clinical Oncology Gastrointestinal Cancers Symposium in San Francisco. Edith Mitchell, M.D., a clinical professor in the Department of Medical …

26
Jan

Jefferson Scientists Discover a Key Protein Regulator of Inflammation and Cell Death

Reporting in the journal Nature, researchers led by Emad Alnemri, Ph.D., professor of Biochemistry and Molecular Biology in the Kimmel Cancer Center at Jefferson, discovered a key protein component involved in inflammation. The protein, AIM2 (absent in melanoma 2), is involved in the detection and reaction to dangerous cytoplasmic DNA that is produced by infection …

26
Jan

African-Americans Have Worse Prognosis Compared to Caucasians When Diagnosed With Colorectal Cancer

African-American patients with colorectal were more likely to present with worse pathological features at diagnosis and to have a worse five-year survival rate compared to Caucasian patients, according to a study conducted by researchers at Thomas Jefferson University. The results are being presented at the 2009 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium. …

5
Dec

A Place for Me

The Kimmel Cancer Center at Jefferson hosted “A Place for Me” in Bluemle Life Science Building on Saturday, November 10, 2007. A family program, “A Place for Me” supports and educates children whose parents or grandparents have cancer. The November program featured art, games, and storytelling to help children understand the disease process, and to …

19
Nov

Navigating the New Normal

Cartoon Boot Camp Tongue cancer survivor Christian “Patch” Patchell lead a “Cartoon Boot Camp” for young adult survivors on October 25, 2008. This innovative program, held in Hamilton Building, focused on using art as a tool to manage difficult feelings associated with cancer treatment and survivorship. A graphic artist and art instructor at University of …

7
Nov

Therapy May Block Expansion of Breast Cancer Cells

Breast cancer stem cells are known to be involved in therapy resistance and the recurrence of cancerous tumors. A new study appearing in Clinical and Translational Science shows the mechanisms governing stem cell expansion in breast cancer (called Notch activity), and finds that therapy targeting a protein called cyclin D1 may block the expansion of …

6
Nov

Dr. Edith Mitchell Receives ‘Tree of Life’ Award

Edith P. Mitchell, M.D., clinical professor, Department of Medical Oncology at Jefferson Medical College of Thomas Jefferson University and associate director of Diversity Programs for the Kimmel Cancer Center at Jefferson, was recently honored with a ‘Tree of Life’ award from The Wellness of You, a local nonprofit health education and resource organization. The ‘Tree …

24
Oct

Nobel Laureate Barry Marshall to Receive the Lennox K. Black International Prize for Excellence in Biomedical Research

Two-day Symposium at Jefferson Will Focus on Transformational Discoveries in Cancer Research Barry Marshall, A.C., an Australian physician and researcher, was convinced that stomach ulcers developed from a bacterial infection and not from stress as commonly believed. In 1984, when working at the Royal Perth Hospital, he tested his theory on himself by drinking a …

24
Sep

Dr. Baserga presents latest findings at the 7th International Symposium on Translational Research in Oncology

Translational scientists from around the globe will assemble in Huntington Beach this October for the 7th International Symposium on Translational Research in Oncology. The program, developed by co-chairs Dennis J. Slamon M.D., Ph.D., and John Crown M.D., M.P.H., includes discussions on the latest translational research developments, to improve the clinical outcomes for cancer patients.

21
Jul

Thomas Jefferson University Hospital Cancer Program Recognized by U.S. News & World Report

The trusted U.S. News & World Report, in its 2008 ratings of America’s Best Hospitals, ranked the Thomas Jefferson University Hospital cancer program among the 50 best in the country. Ranked at number 28, the TJUH cancer program surpassed those of many prestigious institutions. The rankings include over 5,000 hospitals nationally, of which “only 170 …

7
Jul

Jefferson Researchers Show Antibody to Breast Cancer- Secreted Protein Blocks Metastasis

Scientists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have made a key discovery about the mechanism of breast cancer metastasis, the process by which cancer spreads. Focusing on a gene dubbed “Dachshund,” or DACH1, they are beginning to pinpoint new therapeutic targets to halt the spread of cancer. Reporting their findings …

24
Jun

Different Type of Colon Cancer Vaccine Reduces Disease Spread, Jefferson Scientists Show

Taking advantage of the fact that the intestines have a separate immune system from the rest of the body, scientists at the Kimmel Cancer Center at Jefferson in Philadelphia have found a way to immunize mice against the development of metastatic disease. Reporting online Tuesday, June 24, 2008 in the Journal of the National Cancer …

18
Jun

Blocking Signaling Protein Prevents Prostate Cancer Spread, Jefferson Scientists Find

Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia have shown that by blocking a signaling protein, they can prevent prostate cancer cells from metastatic dissemination. The work opens the door to future studies examining the protein as a target for therapies aimed at keeping prostate cancer at bay. In a series of experiments …

18
Jun

Jefferson, Ohio State Team Find Gene Signature Profile for Metastasis

A common signature of tiny, specific pieces of non-coding genetic material known as microRNAs (miRNAs) may be directly involved in the spread of cancer to other parts of the body. Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia and Ohio State University Medical Center in Columbus have identified such a signature, made up …

3
Jun

Monitoring Blood Flow Helps Improve Prostate Biopsies, Jefferson Researchers Report

Using a special ultrasound technique to spot areas of blood flow in the prostate gland may substantially reduce the number of unnecessary biopsies, according to a new study by urologists and radiologists at the Jefferson Prostate Diagnostic Center and the Kimmel Cancer Center at Jefferson in Philadelphia. The researchers found that biopsies targeted to areas …

23
May

Traditional Herbal Medicine Kills Pancreatic Cancer Cells, Kimmel Cancer Center at Jefferson Researchers Report

An herb used in traditional medicine by many Middle Eastern countries may help in the fight against pancreatic cancer, one of the most difficult cancers to treat. Researchers at the Kimmel Cancer at Jefferson in Philadelphia have found that thymoquinone, an extract of Nigella sativa seed oil, blocked pancreatic cancer cell growth and killed the …

14
Apr

Kimmel Cancer Center Scientist Elected to Interurban Clinical Club

Michael Lisanti, M.D., Ph.D., has recently been elected membership to the Interurban Clinical Club. This prestigious club was founded by Sir William Osler in 1905 for the purpose of exchanging ideas and fellowship among medical teachers in some of the leading Eastern medical schools. Dr. Lisanti, joins existing members of the Interurban Clinical Club, Dr. …

14
Apr

Jefferson Scientists’ Discovery May Help Explain Smoking-Pancreatic Cancer Link

If lung cancer and heart disease aren’t bad enough, cigarette smokers are also at higher risk for developing, among other things, pancreatic cancer. Now, researchers at the Kimmel Cancer at Jefferson in Philadelphia have preliminary evidence indicating one possible reason why. Data being presented April 13, 2008 during the Annual Meeting of the American Association …

14
Apr

Neal Flomenberg, M.D., Named Chair of the Department of Medical Oncology at Jefferson

Bone marrow transplant expert Neal Flomenberg, M.D., has been named the new chair of the Department of Medical Oncology at Jefferson Medical College of Thomas Jefferson University, Thomas Jefferson University Hospital and the Kimmel Cancer Center at Jefferson in Philadelphia. Dr. Flomenberg, who is also Clinical Deputy Director at the Kimmel Cancer Center and professor …

14
Apr

Blood Pressure Drugs Halt Pancreatic Cancer Cell Growth, Jefferson Researchers Find

Researchers at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia are inching closer to understanding how common blood pressure medications might help prevent the spread of pancreatic cancer. They have found in the laboratory that one type of pressure-lowering drug called an angiotensin receptor blocker inhibits pancreatic cancer cell growth and causes cell …

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