18
Aug

Colorectal Cancer Metastasis: A Game of Clones

Colorectal cancer is highly prevalent worldwide, and metastasis of colorectal cancer to distant sites accounts for ~90% of the mortality associated with this disease. Researchers at the Sidney Kimmel Cancer Center at Jefferson (SKCC), along with collaborators at several other institutions, tracked genomic changes that occur as colorectal tumors progress and metastasize to distant sites …

10
Aug

Cancer Immunotherapy Might Come with a Hidden Cost

Recent findings from investigators at the Sidney Kimmel Cancer Center at Jefferson raise potential concerns regarding adverse effects associated with a therapeutic approach that has revolutionized the field of cancer treatment — cancer immunotherapy. The findings were recently published in the International Journal of Radiation Oncology + Biology + Physics. In immunotherapy, clinicians harness the power of …

9
Aug

Thomas Jefferson University Hospital (Sidney Kimmel Cancer Center at Jefferson) Ranked No. 20 in the Nation for Cancer

Thomas Jefferson University Hospital (Sidney Kimmel Cancer Center at Jefferson) has been nationally ranked No. 20 in the cancer specialty for 2017-2018 by U.S. News & World Report. U.S. News & World Report Best Hospitals rankings recognize hospitals that treat the most challenging patients and evaluate each hospital’s use of advanced technologies, safety, outcomes, and …

4
Aug

Researchers Developing Strategy to Optimize Personalized Therapy for Pancreatic Cancer

New research from investigators at the Sidney Kimmel Cancer Center at Jefferson provides insight into a cellular mechanism underlying the ability of pancreatic cancer cells to resist a promising, personalized therapy. The study was recently published online in Cancer Research. The research team studied the role of an RNA-binding protein termed HuR in influencing the …

2
Aug

Abington – Jefferson Health Recognized by NRG Oncology

Congratulations to Abington – Jefferson Health, who was recently announced as the #3 top accruing Main Member site for Fiscal Year 2017 by NRG Oncology. The announcement was made at the NRG Oncology Semiannual Meeting, held July 13-15, 2017 in Philadelphia. NRG Oncology seeks to improve the lives of patients with cancer by conducting practice-changing …

26
Jul

Single-Cell Resolution Mutational Profiling in Breast Cancer

A new study from Sidney Kimmel Cancer Center at Jefferson demonstrated the feasibility of detecting cancer-associated gene mutations in circulating tumor cells (CTC) isolated from patients — providing a powerful new tool for clinicians and cancer researchers. Published in Clinical Cancer Research, the project was led by senior authors Paolo M. Fortina, MD, PhD, and Massimo …

14
Jul

A Lifelong Dedication to Cancer

When Alison Petok was five years old, her Nana died of leukemia. “If she had been diagnosed a decade or two later, perhaps she would have survived due to the advances in blood cancer research,” Alison reflected. Years later in 2017, Alison was nominated as “Woman of the Year” by The Leukemia & Lymphoma Society …

11
Jul

Understanding Chemotherapy Resistance in Pancreatic Cancer

A collaborative study involving Sidney Kimmel Cancer Center at Jefferson (SKCC) investigators, together with colleagues from the University of California at San Diego, has provided important insights into how pancreatic cancer cells are able to resist the effects of chemotherapeutic agents. The new study, published in Cancer Research, was led by senior author Jordan Winter, MD, FACS, Associate Professor of …

23
Jun

Important New Insights into Key Regulatory Pathway for Cancer Cell Survival

New research from the laboratory of Christine Eischen, PhD, Co-Leader of the Molecular Biology and Genetics Program at the Sidney Kimmel Cancer Center at Jefferson, has revealed a previously unappreciated feature of a well-known cell survival mechanism with potentially important implications for the treatment of some cancers. The study, recently published in Cancer Research, focuses on the …

5
May

Getting Personal about Inherited Risk for Prostate Cancer

A new study published in JCO Precision Oncology by lead investigator Veda N. Giri, MD, at the Sidney Kimmel Cancer Center at Jefferson takes an important step in deciphering the genetic landscape contributing to inherited prostate cancer. Genetic Evaluation of Men (GEM) is a study focused on uncovering the genetic contribution to inherited prostate cancer. …

4
May

Kathleen O’Doherty Joins SKCC In Joint Navigator Position

We are excited to announce that Kathleen O’Doherty, RN, BSN, OCN, has joined us in the role of Nursing Care Coordinator: Oncology Outreach, a joint navigator position between Main Line Health Cancer Care and The Sidney Kimmel Cancer Center at Jefferson. Kathleen will work closely with physicians and members of the multidisciplinary care teams at both institutions …

1
May

Dr. Veda Giri Featured on Congressional Directed Medical Research Programs Website

The research of Sidney Kimmel Cancer Center investigator Veda Giri, MD, has been highlighted on the Congressionally Directed Medical Research Programs (CDMRP) website. Giri and her team received funding from the U.S. Department of Defense Prostate Cancer Research Program (PCRP) to conduct studies on men at high risk for aggressive prostate cancer.  She and her …

28
Apr

Opening Up Chromatin for Cell Differentiation

Two new studies from the laboratory of Alex Mazo, PhD, at the Sidney Kimmel Cancer Center, along with collaborators from SKCC, the Vickie and Jack Farber Institute for Neuroscience at Thomas Jefferson University, and other institutions, provide new insights into the structure of chromatin and its implications for cellular differentiation.  The new work, appearing in …

25
Apr

New Insights into G Protein-Coupled Receptor Signaling and Regulation

A collaborative study by the laboratories of Jeffrey L. Benovic, PhD,  in the Department of Biochemistry and Molecular Biology at Thomas Jefferson University and the Sidney Kimmel Cancer Center at Jefferson, and Dr. Brian K. Kobilka in the Department of Molecular and Cellular Physiology at the Stanford University School of Medicine provides new insights into a …

5
Apr

Promising New Results in Lung Cancer Research

Investigators at the Sidney Kimmel Cancer Center at Jefferson have uncovered a new regulatory pathway with important implications for lung cancer. Lung cancer is the leading cause of all cancer-related deaths worldwide, with 85% of all cases consisting of non-small cell lung cancer (NSCLC). A major obstacle to successfully treating NSCLC  is that many patients …

30
Mar

2017 Ocular Melanoma Foundation–AACR Fellowship Awarded to Vivian Chua

The Sidney Kimmel Cancer Center at Jefferson is pleased to announce that Vivian Chua, PhD, has been awarded a 2017 Ocular Melanoma Foundation–American Associate for Cancer Research (AACR) Fellowship for her project, “Novel Epigenetic Targeting Approaches in Uveal Melanoma.” This one-year, $50,000 grant recognizes the significant impact of Dr. Chua’s research, its relevance to the …

29
Mar

Christine Bonaccorso Named Administrative Director of Sidney Kimmel Cancer Network

Please join us in congratulating Christine Bonaccorso, RN, BSN, OCN, on assuming the position of Administrative Director of the Sidney Kimmel Cancer Network. Over the past several months, Bonaccorso has proven to be an outstanding leader while serving as Interim Director, playing a critical role in several projects that have greatly enhanced the Cancer Network. …

24
Mar

Noelle Williams Inducted into Gold Humanism Honor Society

The Sidney Kimmel Cancer Center at Jefferson would like to congratulate Noelle L. Williams, MD, who has been selected for induction into the Gold Humanism Honor Society Resident Chapter of Thomas Jefferson University. The Gold Humanism Honor Society recognizes students, residents, and faculty who are exemplars of compassionate patient care and who serve as role …

23
Mar

Ralph Zinner and Amy Leader Awarded ACT Research Grant from Free to Breathe

The Sidney Kimmel Cancer Center at Jefferson is pleased to announce that Ralph Zinner, MD, and Amy Leader, DrPH, MPH, are the winners of the second Accelerate Clinical Trials (ACT) Research Grant Award from Free to Breathe, an organization devoted to improving the treatment and survival of lung cancer patients.  The ACT grant is a funding …

21
Mar

Unite for HER Wellness Day – April 2, 2017

  The Sidney Kimmel Cancer Center at Jefferson encourages Jefferson Hospital System breast cancer patients to participate in the upcoming “Unite for HER Wellness Day” event to be held on Sunday, April 2, 2017. This event will allow breast cancer patients to meet in a small group setting with trained professionals to learn about complementary …

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